SYNTHESIS OF 'HIGH-MANNOSE' OLIGOSACCHARIDE MIMICS

机译：“高甘露糖”寡糖模拟的合成

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High-mannose type N-glycans are well known to participate in quality control and intracellular traffic of glycoproteins. They cover the surface of many pathogenic microorganisms and are the targets of the immune system cells through their mannose receptors. They are characterized by the presence of two to six mannose residues linked to the common pentasaccharidic core Mana(1-6) [Manα(1-3)]Manβ(1-4)GlcNAcβ(1-4)GlcNAc.

机译：“高甘露糖”型N-聚糖是众所周知的，参与糖蛋白的质量控制和细胞内交通。它们覆盖了许多致病微生物的表面，并且是免疫系统细胞通过甘露糖受体的靶标。它们的特征在于，存在与常见的戊糖核心法（1-6）[MANα（1-3）]MANβ（1-4）GLCNACβ（1-4）GLCNAc连接的两到六个甘露糖残基。

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《International Carbohydrate Symposium》|2013年||共1页
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Francois-Heude. M.; Cendret V.; Mendez-Ardoy A.;
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中图分类天然化合物;
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1. Synthesis of High-Mannose Oligosaccharide Analogues through Click Chemistry: True Functional Mimics of Their Natural Counterparts Against Lectins? [J] . Francois-Heude Marc, Mendez-Ardoy Alejandro, Cendret Virginie, Chemistry: A European journal . 2015,第5期

机译：通过单击化学合成高甘露糖寡糖类似物：天然抗凝集素的真正功能模拟物吗？
2. Design and synthesis of a 'click' high-mannose oligosaccharide mimic emulating Man8 binding affinity towards Con A [J] . Virginie Cendret, Marc Francois-Heude, Alejandro Mendez-Ardoy, Chemical Communications . 2012,第31期

机译：设计和合成“点击”高甘露糖寡糖模拟物模拟Man8对Con A的结合亲和力
3. Efficient synthesis of glycopeptide-α-thioesters with a high-mannose type oligosaccharide by means of tert-Boc-solid phase peptide synthesis [J] . Makimura Y., Kiuchi T., Izumi M., Carbohydrate research . 2012,第Null期

机译：通过叔-Boc-固相肽合成有效合成具有高甘露糖型寡糖的糖肽-α-硫酯
4. SYNTHESIS OF 'HIGH-MANNOSE' OLIGOSACCHARIDE MIMICS [C] . Francois-Heude. M., Cendret V., Mendez-Ardoy A. International Carbohydrate Symposium . 2013

机译：“高甘露糖”寡糖模拟的合成
5. Application of olefin metathesis reaction towards the synthesis of oligosaccharide mimics: A novel strategy in chemical glycobiology. [D] . Dominique, Romyr. 2003

机译：烯烃复分解反应在寡糖模拟物合成中的应用：化学糖生物学的新策略。
6. Glycoprotein biosynthesis in animal cells grown in suspension culture. Assembly of lipid-linked saccharides and formation of protein-bound 'high-mannose' oligosaccharides. [O] . D S Bailey, J Burke, R Sinclair, 2011

机译：在悬浮培养中生长的动物细胞中糖蛋白的生物合成。脂质连接糖的组装和蛋白质结合的“高甘露糖”寡糖的形成。
7. Synthesis of high-mannose oligosaccharide analogues through click chemistry: True functional mimics of their natural counterparts against lectins? [O] . François-Heude M., Méndez-Ardoy Alejandro, Cendret V., 2015

机译：通过点击化学合成高甘露糖寡糖类似物：其天然对应物针对凝集素的真实功能模拟物？

SYNTHESIS OF 'HIGH-MANNOSE' OLIGOSACCHARIDE MIMICS

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