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NEW INSIGHTS INTO STREPTOCOCCUS PNEUMONIAE LIPOTEICHOIC ACID STRUCTURE AND FUNCTION

机译：肺炎链球菌脂素酸的结构和功能的新见解

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Besides peptidoglycan and lipoproteins, wall teichoic acids (WTA) and lipoteichoic acids (LTA) are the major constituents of the Gram-positive cell wall. Streptococcus pneumoniae possesses a - in comparison to other Gram-positive bacteria - structurally unique, complex LTA which is highly decorated with phosphorylcholine (ChoP) residues. Pneumococcal teichoic acids (pnTA) play an important role in bacterial survival, growth and pathogenicity. For example, the ChoP residues serve as anchors for surface-located choline-binding proteins (CBPs), which have immunoprotective potential or are involved in essential physiological functions like cell wall turnover and bacterial adhesion.

机译：除了肽聚糖和脂蛋白外，壁噻吩酸（WTA）和脂脂酸（LTA）是革兰阳性细胞壁的主要成分。链球菌肺炎料与其他革兰氏阳性细菌（结构独特）的含量独特，复合LTA相比，其高度装饰着磷酸胆碱（Chec）残留物。肺炎球菌噻吩（PNTA）在细菌存活，生长和致病性中起重要作用。例如，Chec残基用作表面定位的胆碱结合蛋白（CBP）的锚，其具有免疫保护潜力或参与细胞壁周转和细菌粘附等必要的生理功能。

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《International Carbohydrate Symposium》|2013年||共1页
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Gisch. N.; Kohler T.; Ulmer A. J.;
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1. Lipoteichoic acid of Streptococcus oralis Uo5: a novel biochemical structure comprising an unusual phosphorylcholine substitution pattern compared to Streptococcus pneumoniae [J] . Nicolas Gisch, Dominik Schwudke, Simone Thomsen, Scientific reports. . 2015,第1期

机译：口腔链球菌Uo5的脂磷壁酸：一种新颖的生化结构，与肺炎链球菌相比，它具有不寻常的磷酸胆碱取代模式
2. Structural Reevaluation of Streptococcus pneumoniae Lipoteichoic Acid and New Insights into Its Immunostimulatory Potency [J] . Nicolas Gisch, Thomas Kohler, Artur Ulmer, The Journal of biological chemistry . 2013,第22期

机译：肺炎链球菌脂脂素的结构重新评估，并进入其免疫刺激性效力的新见解
3. Total Synthesis of the Lipid-Anchor-Attached Core Trisaccharides of Lipoteichoic Acids of Streptococcus pneumoniae and Streptococcus oralis Uo5 [J] . Ghotekar Balasaheb K., Podilapu Ananda Rao, Kulkarni Suvarn S. Organic letters . 2020,第2期

机译：肺炎链球菌脂脂酸碱酸脂纤维纤维三糖的总合成及链球菌Oralis UO5
4. NEW INSIGHTS INTO STREPTOCOCCUS PNEUMONIAE LIPOTEICHOIC ACID STRUCTURE AND FUNCTION [C] . Gisch. N., Kohler T., Ulmer A. J. International Carbohydrate Symposium . 2013

机译：肺炎链球菌脂素酸的结构和功能的新见解
5. Investigation of lipoteichoic acid structure and function to establish its role in Gram-positive bacterial infections. [D] . Seo, Ho Seong. 2008

机译：调查脂蛋白酸的结构和功能以确立其在革兰氏阳性细菌感染中的作用。
6. Corrigendum: Lipoteichoic acid of Streptococcus oralis Uo5: a novel biochemical structure comprising an unusual phosphorylcholine substitution pattern compared to Streptococcus pneumoniae [O] . Nicolas Gisch, Dominik Schwudke, Simone Thomsen, -1

机译：更正：口腔链球菌Uo5的脂蛋白酸：一种新型的生化结构与肺炎链球菌相比具有不寻常的磷酸胆碱取代模式
7. Structural Reevaluation of Streptococcus pneumoniae Lipoteichoic Acid and New Insights into Its Immunostimulatory Potency [O] . Nicolas Gisch, Thomas Kohler, Artur J. Ulmer, 2013

机译：肺炎链球菌脂脂素的结构重新评估，并进入其免疫刺激性效力的新见解

NEW INSIGHTS INTO STREPTOCOCCUS PNEUMONIAE LIPOTEICHOIC ACID STRUCTURE AND FUNCTION

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