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Monte Carlo simulation study on the time resolution of a PMT-quadrant-sharing LSO detector block for time-of-flight PET

机译:Monte Carlo仿真研究关于飞行时间宠物的PMT - 象限分享LSO检测器块的时间分辨率研究

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We developed a detailed Monte Carlo simulation method to study the time resolution of time-of-flight positron emission tomography (TOF PET). The process of scintillation light emission and transport inside the detector, the photoelectron generation and anode signal generation in the photomultiplier tube (PMT), and the electronics process of discriminator are simulated. We tested this simulation method using published experimental data, and found that it can generate reliable results. Using this method, we simulated the time resolution for a 13x13 detector block of 4x4x20 mm3 lutetium orthosilicate (LSO) crystals coupled to four 2-inch PMTs using PMT-quadrant-sharing (PQS) technology. We analyzed the effects of several factors, including the number of photoelectrons, light transport, transit time spread (TTS), transit time difference between center and edge of the PMT photocathode (ΔtC-E), and the depth of interaction (DOI). The simulation results indicated that system time resolution of 300-350ps should be possible with currently available fast PMTs. This simulation method can also be used to simulate the time resolution of other detector design method.
机译:我们开发了一种详细的蒙特卡罗仿真方法,研究飞行时间正电子发射断层扫描(TOF PET)的时间分辨率。模拟了闪烁发光和传输,光电倍增管(PMT)中的光电子发电和阳极信号的传输,以及鉴别器的电子过程。我们使用已发布的实验数据测试了此模拟方法,并发现它可以产生可靠的结果。使用该方法,我们模拟了使用PMT - 象限共享(PQS)技术的4×4×20mm 3℃的13x13检测器块的时间分辨率为4×4×20mm 3℃的3×4x20mm 3 / sop> rutetium(Lso)晶体。我们分析了若干因素的影响,包括光电子的数量,光传输,运输时间扩展(TTS),PMT光电阴极的中心和边缘之间的过渡时间差(Δt ce ),以及深度互动(DOI)。仿真结果表明,应有300-350PS的系统时间分辨率,目前可用的快速PMTS应该是可能的。该模拟方法还可用于模拟其他检测器设计方法的时间分辨率。

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