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Feasibility of using beta-gamma coincidence for 3D PET attenuation correction

机译:使用Beta-Gamma巧合3D宠物衰减校正的可行性

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Better attenuation correction is needed in 3D PET in order to reduce image noise. It is well known that positrons must lose an appreciable amount of energy before annihilation with an electron can occur. If this energy is lost in a plastic scintillator or PIN photo-diode it can provide a "start pulse" to a coincidence circuit, while the conventional PET detectors provide a stop pulse and identify the line of response. Cheaper, non-positron emitting isotopes, which decay by beta-gamma cascade, (eg Co-60) could also be used. We have shown that the energy loss of positrons emitted from F- 18 can be detected with a PIN diode. The recorded energy is above the noise for most events, and the timing spectrum from a PIN diode detecting the positron and an LSO crystal detecting the gamma ray show excellent timing resolution. A narrow coincidence window allows high count rates. Multiple sources and post-injection scans can be used. Based on preliminary data presented here it should be possible to adapt this technique to modem PET scanners which now use 2D acquisitions, and extended septa only for performing transmission scans.
机译:3D PET需要更好的衰减校正以降低图像噪声。众所周知,在用电子可能发生湮灭之前,正水必须失去明显的能量。如果在塑料闪烁体或引脚光电二极管中丢失这种能量,则可以向重合电路提供“开始脉冲”,而传统的PET检测器提供停止脉冲并识别响应线。也可以使用更便宜的非正电子发射同位素,其β-gamma级联(例如CO-60)衰减。我们已经表明,可以通过引脚二极管检测从F-18发出的正核的能量损失。记录的能量高于大多数事件的噪声,以及来自检测正电子和检测伽马射线的引脚二极管的定时频谱显示出良好的定时分辨率。一个狭窄的巧合窗口允许高计数速率。可以使用多种来源和注射后扫描。基于此处呈现的初步数据,应该可以使该技术调整到Modem PET扫描仪,该宠物扫描仪现在使用2D采集,并仅用于执行传输扫描的扩展隔间。

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