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首页> 外文会议>Mediterranean Conference on Medical and Biological Engineering and Computing >Closed-Loop Modulation of a Notch-Filter Stimulation Strategy for Tremor Management with a Neuroprosthesis
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Closed-Loop Modulation of a Notch-Filter Stimulation Strategy for Tremor Management with a Neuroprosthesis

机译：闭环调制对震颤滤波器刺激策略与神经调节作用

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Tremor is the most common movement disorder, and one of the major causes of functional disability. In spite of the existence of various treatments, tremor is not managed effectively in a large number of patients, which make it a major cause of loss of quality of life. Here we present a novel strategy for tremor suppression through neurostimulation that replicates an adaptive notch-filter at the frequency of the tremor. The controller, which adapts the neurostimulation to the ongoing amplitude, frequency and phase of the tremor, is implemented in a wearable neuroprosthesis for tremor management. Experimental results in one patient with severe essential tremor illustrate the interest of the approach.
机译：震颤是最常见的运动障碍，以及功能性残疾的主要原因之一。尽管存在各种治疗，但在大量患者中没有有效管理震颤，这使得它成为生命质量丧失的主要原因。在这里，我们通过神经刺激提出了一种新的震颤抑制策略，该刺激通过在震颤的频率下复制自适应凹口滤波器。适用于对震颤的持续振幅，频率和相位的神经刺激的控制器在震颤管理的可穿戴神经调节中实现。一个严重基本震颤的一名患者的实验结果表明了这种方法的兴趣。

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