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Digital image processing for the early localization of cancer

机译:癌症早期本地化的数字图像处理

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The prognosis for cancer patients becomes much better if a tumor is diagnosed, localized and treated early, in a precancerous stage. The difficulty lies in the localization of cancerous tumors. Carcinoma in situ (CIS) refers to a tumor which is approximately 100 microns thick and one which has not penetrated through the epithelium wall or become invasive (2). A tumor of this size cannot be detected by existing techniques such as x-ray, computer tomography, magnetic resonance imaging, nuclear medicine or conventional endoscopy under white-light illumination. However, these tumors can be localized and destroyed by photodynamic diagnosis and therapy. This research shows that digital image processing and the technique of digital image ratioing contribute to photodynamic diagnosis and the early localization of cancer. A software package has been developed as a result of this research. The software package quantifies the usefulness of digital image processing for tumor localization and detectability. System parameters such as the endoscope distance and angle variations, tumor size and tumor concentration, sensitivity and specificity of the system have been tested and quantified.
机译:如果肿瘤被诊断,局部化和治疗,在癌前阶段,癌症患者的预后变得更好。困难在于癌症肿瘤的定位。原位(顺式)的癌是指大约100微米厚的肿瘤,肿瘤,其尚未穿过上皮壁或被侵入(2)。在白光照明下,现有技术不能通过现有技术检测这种尺寸的肿瘤,例如X射线,计算机断层扫描,磁共振成像,核医学或常规内窥镜检查。然而,这些肿瘤可以通过光动力诊断和治疗局部和破坏。本研究表明,数字图像处理和数字图像比的技术有助于光动力诊断和癌症的早期定位。由于这项研究,已经开发了一种软件包。软件包量化了数字图像处理的有用性,以了解肿瘤定位和可检测性。系统参数,例如内窥镜距离和角度变化,肿瘤大小和肿瘤浓度,敏感性和敏感性和特异性已经过测试和定量。

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