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On the features and assumptions of bone remodelling theories part 1: stability analysis and selection of remodelling stimulus

机译:关于骨改造理论的特征和假设第1部分:稳定性分析与重塑刺激的选择

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The conditions on the value of m and n for stability of the process are expected. For a stable process, the stimulus S(Φ) is a decreasing function of the density Φ (e.g., as in Eq. 5 when m > n), and the rate of change in density (partial derivΦ)/(partial deriv t) is an increasing function of the stimulus (i.e., (partial deriv Φ)/(partial deriv S) > 0). Therefore, the process is able to reach an adaptation equilibrium. In Part II, the process will be simulated and the influence of themagnitude of m and n on the computed density will be shown. It is worth noting here that only the particular geometry of a long bone diaphysis has been considered in the present study, so that the conditions for stability should be viewed as necessary but not sufficient.The similarity of the change in density and geometry independent of the stimulus is not unexpected as the different stimuli are all dependent quantities. Therefore, simulation of the BRP demands greater attention on its stability characteristics than thechoice of the stimulus.
机译:预期对该过程稳定性的M和N值的条件。对于稳定的过程,刺激S(φ)是密度φ的降低函数(例如,当M> n时5)的函数,以及密度的变化率(部分erivφ)/(部分deriv t)是刺激的越来越多的函数(即(部分erivφ)/(部分eriv s)> 0)。因此,该过程能够达到适应平衡。在第二部分中,将被模拟该过程,并显示M和N对计算密度的影响。这里值得注意的是,在本研究中仅考虑了长骨晶体的特定几何形状,从而应根据需要观察稳定性的条件但不足。密度和几何变化的相似性独立于由于不同的刺激是所有依赖的数量,刺激并不出乎意料。因此,BRP的仿真要求对其稳定性特性的更大关注而不是刺激的Thoce。

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