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首页> 外文会议>NATO advanced study conference on polymer based systems on tissue engineering, replacement and regeneration >CHARACTERIZATION OF DEGRADABLE POLYMERS FOR ORTHOPEDIC APPLICATION Examining Tyrosine-Derived Polycarbonates for Tissue Engineering of Bone
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CHARACTERIZATION OF DEGRADABLE POLYMERS FOR ORTHOPEDIC APPLICATION Examining Tyrosine-Derived Polycarbonates for Tissue Engineering of Bone

机译：用于骨透析术治疗酪氨酸衍生聚碳酸酯的可降解聚合物的表征

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As tissue engineering conies to the forefront as a cutting-edge discipline, one of the principle challenges is the need for new materials that are fully bioresorbable and biocompatible. To this extent, pseudo-poly(amino acid)s such as tyrosine-derived polycarbonates present themselves as a promising new class of degradable polymers. These materials offer a high degree of bone biocompatibility. Varations in pendent chain structure allow the generation of a series of materials with variations in key mechanical and cellular response properties. In addition, their chemical structure provides convenient attachment points for the covalent linkage of bioactive molecules to the polymer backbone. Tyrosine-derived polycarbonates can be shaped by commonly used processing and fabrication methods - another advantage over conventional poly(amino acid)s which are often non-processible.
机译：作为组织工程与前沿的锥体作为尖端纪律，其中一个原则挑战之一是需要全新的新材料，这些材料是完全生物可吸收和生物相容性的。在这种程度上，诸如酪氨酸衍生的聚碳酸酯的伪聚（氨基酸）S如酪氨酸衍生的聚碳酸酯本身作为有希望的新类可降解聚合物。这些材料提供高度骨骼生物相容性。垂体链结构的变化允许产生具有钥匙机械和蜂窝响应性的变化的一系列材料。此外，它们的化学结构为生物活性分子与聚合物主链的共价连接提供了方便的附着点。酪氨酸衍生的聚碳酸酯可以通过常用的加工和制造方法形状 - 常规聚（氨基酸）S的另一个优点是通常是不可加工的。

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