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Monitoring of Endocrine Disruptors in Transgenic Plants Carrying Aryl Hydrocarbon Receptor and Estrogen Receptor Genes

机译：携带芳基烃受体和雌激素受体基因的转基因植物内分泌破坏剂的监测

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Transgenic plants carrying mammalian hormone receptor genes were examined for monitoring of environmental chemicals including dioxins and endocrine disruptors. The transgenic tobacco plants expressing mouse arylhydrocarbon receptor gene detected lppb of the dioxin-like compound 20-methylcholanthrene in the cultured plants. In addition, the transgenic Arabidopsis plants expressing human estrogen receptor gene detected lppt of 178-estradiol and ppb levels of the other endocrine disruptors such as bisphenol A, 4-f-octylphenol, and others in potted plants. These transgenic plants appear to be useful for on site monitoring of dioxins and estrogenic contaminants in the environment.

机译：检查携带哺乳动物激素受体基因的转基因植物，用于监测环境化学品，包括二恶英和内分泌破坏剂。表达小鼠芳基烃受体基因的转基因烟草植物检测到培养的植物中的二恶蛋白样化合物20-甲基蒽的LPPB。此外，表达人雌激素受体基因的转基因拟南芥植物检测到178-雌二醇和PPB水平的LPPT，例如双酚A，4-F-辛基苯酚等盆栽植物中的其他内分泌破坏剂。这些转基因植物似乎有助于在环境中对二恶英和雌激素污染物的现场监测。

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《Pan-Pacific Conference on Pesticide Science》|2005年||共8页
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Hideyuki Inui; Hideaki Sasaki; Susumu Kodama; Nam-Hai Chua; Hideo Ohkawa;
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中图分类农业化学;
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1. Assays of polychlorinated biphenyl congeners and co-contaminated heavy metals in the transgenic Arabidopsis plants carrying the recombinant guinea pig aryl hydrocarbon receptor-mediated β-glucuronidase reporter gene expression system [J] . SAYURI SHIMAZU, MASAYA OHTA, HIDEO OHKAWA, Journal of environmental science and health . 2012,第10期

机译：携带豚鼠芳烃受体介导的β-葡萄糖醛酸苷酶报告基因表达系统的转基因拟南芥植物中多氯联苯同源物和共污染重金属的含量测定
2. Recombinant aryl hydrocarbon receptors for bioassay of aryl hydrocarbon receptor ligands in transgenic tobacco plants [J] . Kodama Susumu, Okada Kumiko, Akimoto Keiko, Plant Biotechnology Journal . 2009,第2期

机译：转基因烟草植物中芳基烃受体配体的生物测定的重组芳基烃受体
3. Recombinant aryl hydrocarbon receptors for bioassay of aryl hydrocarbon receptor ligands in transgenic tobacco plants [J] . Hideo Ohkawa, Hideyuki Inui, Kumiko Okada, Plant Biotechnology Journal . 2008,第2期

机译：重组芳烃受体用于转基因烟草植物中芳烃受体配体的生物测定
4. Monitoring of Endocrine Disruptors in Transgenic Plants Carrying Aryl Hydrocarbon Receptor and Estrogen Receptor Genes [C] . Hideyuki Inui, Hideaki Sasaki, Susumu Kodama, Pan-Pacific Conference on Pesticide Science . 2005

机译：携带芳基烃受体和雌激素受体基因的转基因植物内分泌破坏剂的监测
5. Cloning of CDNAs for estrogen receptor alpha, aromatase, and aryl hydrocarbon receptors and environmental effects on gene expression in the painted turtle (Chrysemys picta) and the red-eared slider (Pseudemys scripta) [D] . Marquez, Emily chan 2011

机译：雌激素受体α，芳香化酶和芳基碳氢化合物受体的CDNA的克隆及其对彩绘龟（Chrysemys picta）和红耳滑鼠（Pseudemys scripta）基因表达的环境影响
6. Assays of dioxins and dioxin-like compounds in actually contaminated soils using transgenic tobacco plants carrying a recombinant mouse aryl hydrocarbon receptor-mediated β-glucuronidase reporter gene expression system [O] . Hideyuki Inui, Keiko Gion, Yasushi Utani, -1

机译：使用携带重组小鼠芳烃受体介导的β-葡糖醛酸糖苷酶报道基因表达系统的转基因烟草植物在实际污染的土壤中测定二恶英和二恶英类化合物
7. Indole-3-Carbinol Triggers Aryl Hydrocarbon Receptor-dependent Estrogen Receptor (ER)α Protein Degradation in Breast Cancer Cells Disrupting an ERα-GATA3 Transcriptional Cross-Regulatory Loop [O] . Marconett, Crystal N., Sundar, Shyam N., Poindexter, Kevin M., 2010

机译：吲哚-3-甲醇触发乳腺癌细胞中的芳烃受体依赖性雌激素受体（ER）α蛋白降解，从而破坏ERα-GATA3转录交叉调节环。

Monitoring of Endocrine Disruptors in Transgenic Plants Carrying Aryl Hydrocarbon Receptor and Estrogen Receptor Genes

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