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首页> 外文会议>International Symposium on Energy and Protein Metabolism and Nutrition >Skeletal muscle response to an endotoxin injection followed by malnutrition is similar in low-grade inflamed and non-inflamed old rats
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Skeletal muscle response to an endotoxin injection followed by malnutrition is similar in low-grade inflamed and non-inflamed old rats

机译：对内毒素注射的骨骼肌反应，然后是营养不良的低级发炎和非发炎的旧老鼠类似

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摘要

Skeletal muscle mass is gradually lost during ageing, a process referred to as sarcopenia (Greenlund and Nair, 2003). Ageing is associated with chronic inflammation, whose intensity is very variable within old individuals (Ferracci et al., 2002; Mayotet al., 2007). The age-associated low-grade inflammation has been suggested to contribute to sarcopenia (Roubenoff, 2003). We have recently shown that sarcopenia is not enhanced in low-grade inflamed old rats compared to age-matched non-inflamed rats, when they are maintained in their breeding conditions (Mayot et al., 2006). However, low-grade inflammation could be a factor associated with an increased risk of muscle mass loss in case of any additional stress in old individuals.
机译：在老化期间骨骼肌肿块逐渐丧失，该过程称为Sarcopenia（Greenlund和Nair，2003）。衰老与慢性炎症有关，其强度在老年人内变化非常有变化（Ferracci等，2002; Mayotet al。，2007）。已经提出了患有年龄相关的低级炎症，为SARCOPENIA有助于（Roubenoff，2003）。我们最近表明，与年龄匹配的非发炎大鼠在其繁殖条件下保持术语（Mayot等，2006）时，肌肉病毒在低程度发炎的老鼠中没有增强。然而，低级炎症可能是与旧人任何额外压力的肌肉质量损失的风险增加相关的因素。

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