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首页> 外文会议>European Congress on Tropical Medicine and International Health >Management of Dengue Hemorrhagic Fever/Dengue Shock Syndrome
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Management of Dengue Hemorrhagic Fever/Dengue Shock Syndrome

机译：登革热病的管理/登革休克综合征

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Dengue is a serious public health problem worldwide. Dengue hemorrhagic fever (DHF)/ Dengue shock syndrome (DSS) are severe forms of dengue virus infections. The main hallmark of DHF/DSS is an increase in vascular permeability in the critical/leakage phase resulting in plasma leakage of fluid from the in-travascular compartment to the extravascular space. In less severe cases (nonshock DHF grade I, II) plasma leakage is mild to moderate, and patients will recover spontaneously or shortly after intravenous fluid administration. In more severe cases (DHF grade III, IV; DSS), when plasma loss is critical, hypovolemic shock ensues and can progress rapidly to profound shock. The patient in shock may die within 12- 24 hours if appropriate treatment is not promptly administered. Volume replacement is the mainstay of treatment of DHF/DSS. Proper organization and good triage in the hospital; supplying enough essential equipment and intravenous fluids for the hospital; well-trained medical staff are essential factors to contribute to the reduction of fatality rates in DHF/ DSS. Dengue is a disease complex which includes two distinct syndromes -dengue fever (DF) and dengue haemorrhagic fever (DHF). Dengue shock syndrome (DSS) is a severe form of DHF. It is caused by dengue viruses which belong to the family Flaviviridae; they can be classified in four serotypes (DEN-1, DEN-2, DEN-3 and DEN-4). In the past 15 years, there has been a dramatic increase in the global incidence of dengue and DHF. More than 2.5 billion people are now at risk in over 200 countries worldwide but only a small proportion of cases are reported to the World Health Organization (WHO).
机译：登革热是全世界严重的公共卫生问题。登革热出血热（DHF）/登革休克综合征（DSS）是登革热病毒感染的严重形式。 DHF / DSS的主要标志是临界/泄漏阶段血管渗透性的增加，导致血浆渗漏流体从血管外间隔到血管外空间。在不太严重的情况下（非座子DHF等级I，II）血浆渗漏是轻度至中度的，并且患者将在静脉内流体给药后自发或不久恢复。在更严重的情况下（DHF级III，IV; DSS），当等离子体损失是关键的时，缓冲休克随之而来，可以迅速进展到深远的冲击。如果不及时施用适当的治疗，休克患者可能会在12-24小时内死亡。体积更换是DHF / DSS的治疗的主要支柱。在医院的适当组织和良好的分类;为医院提供足够的必需设备和静脉内液体;训练有素的医务人员是有助于减少DHF / DSS的死亡率的重要因素。登革热是一种疾病复杂，包括两个不同的综合征 - 发烧（DF）和登革热出血热（DHF）。登革船休克综合征（DSS）是一种严重的DHF形式。它是由属于flaviviridae的植物病毒引起的;它们可以分为四种血清型（DEN-1，DEN-2，DEN-3和DEN-4）。在过去的15年里，在登革热和DHF的全球发病率急剧增加。全球200多个国家的超过25亿人患有超过200个国家，但仅向世界卫生组织（世卫组织）报告了一小部分案件。

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