To quantitatively assess the degradation process of biomaterial scaffolds, in-vitro and in-vivo UEI and elastic modulus reconstruction were performed and compared with direct mechanical measurements and weight loss. Preliminary in-vitro and in-vivo results support the feasibility of UEI as a non-invasive monitoring tool of tissue scaffold degradation. This technique can be easily integrated into a commercial ultrasound scanner for real-time in-vivo animal study, possibly for a clinical tool to monitor the soft tissue growth and scaffold degradation.
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