• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>International Conference on Perspectives in Vibrational Spectroscopy >FT-IR Spectroscopic Analysis of Normal andMalignant Human Oral Tissues
【24h】

FT-IR Spectroscopic Analysis of Normal andMalignant Human Oral Tissues

机译：正常和靶向人口组织的FT-IR光谱分析

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

FT-IR spectroscopy has been used to explore the changes in the vibrational bands ofnormal and oral squamous cell carcinoma (OSCC) tissues in the region 4000-400 cm~(-1).Significant changes in the spectral features were observed. The spectral changes were the resultsof characteristics structural alterations at the molecular level in the malignant tissues. Thesealterations include structural changes of proteins and possible increase of its content, an increasein the nucleic-to-cytoplasm ratio, an increase in the relative amount of DNA, an increase in therate of phosphorylation process induced by carcinogenesis, a loss of hydrogen bonding of theC-OH groups in the amino acid residues of proteins, a decrease in the relative amount of lipidscompared to normal epithelial oral tissues. The results of the present study demonstrate that theFT-IR technique has the feasibility of discriminating malignant from normal tissues and otherpathological states in a short period of time and may detect malignant transformation earlier thanthe standard histological examination stage.
机译：FT-IR光谱已被用于探讨区域4000-400cm〜（-1）中正常和口腔鳞状细胞癌（OSCC）组织的振动带的变化。观察到光谱特征的显着变化。光谱变化是恶性组织中分子水平的结构改变的结果。 Chesealations包括蛋白质的结构变化和可能的含量的增加，增加核 - 胞质核的比例，DNA相对量的增加，致癌物质诱导的磷酸化过程的增加，Thec的氢键丧失-OH基团在蛋白质的氨基酸残基中，对普通上皮口组织的脂质相对的相对量的降低。本研究结果表明，灌注IR技术具有在短时间内从正常组织和种类特性状态判断恶性的可行性，并且可能检测到早期的刺骨标准组织学检查阶段的恶性转化。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号