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Analog CMOS Charge Model for Molecular Redox Electron-Transfer Reactions and Bio-Chemical Pathways

机译:用于分子氧化还原电子转移反应和生物化学途径的模拟CMOS电荷模型

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Oxidation and reduction (Redox) reactions are known to constitute an electron transfer chain in many bio-chemical pathways in living organisms (systems). Mathematical modeling of these bio-chemical pathways is of growing focus in the emerging area of systems biology. In this brief paper an effort is made to develop a CMOS integrated circuit model for the electron transfer chain in the biochemical pathway of bio-cellular mitochondrial respiration. Integrated circuit models for protons (H+), neutral oxygen, reduced oxygen (oxygen an-ion), water (H_(2)O) molecule formation, oxidation and reduction of molecules has been developed in the process. This new technique compares favorably to other mathematical modeling efforts in systems biology for signaling and metabolic pathways in bio-cells.
机译:已知氧化和还原(氧化还原)反应构成生物体(系统)中许多生物化学途径中的电子转移链。这些生物化学途径的数学建模在于系统生物学的新兴地区越来越赘兆。在本简要论文中,努力开发用于生物细胞线粒体呼吸的生化途径中的电子转移链的CMOS集成电路模型。用于质子(H +),中性氧,减少氧气(氧气 - 离子),水(H_(2)O)分子形成,氧化和分子的氧化分子的集成电路模型已经在该过程中开发。这种新技术对系统生物学中的其他数学建模工作有利地比较了生物细胞中的信号和代谢途径。

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