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首页> 外文会议>IASTED international conference on nanotechnology and applications >SAFE WORK WITH NANOPARTICLES THROUGH AN OCCUPATIONAL RISK MANAGEMENT APPROACH AND A PREVENTION PROGRAM
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SAFE WORK WITH NANOPARTICLES THROUGH AN OCCUPATIONAL RISK MANAGEMENT APPROACH AND A PREVENTION PROGRAM

机译：通过职业风险管理方法和预防计划使用纳米颗粒安全使用

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摘要

Engineered nanoparticles (NPs) are developed in research laboratories and produced in industrial plants, where the most extensive exposures are likely to occur. Many toxicological studies have demonstrated various specific health risks related to the absorption of NPs but data are still limited and numerous uncertainties remain. On a mass basis, NPs are normally more toxic than the same substances in larger dimensions. These particles show size-dependent adverse biological effects, and occupational exposure must be maintained as low as possible. Our visits to occupational settings demonstrate that many workers are not aware of the potential risks and, in many situations, do not implement appropriate procedures to limit occupational exposure to these products. This article proposes a framework for occupational risk management with the objective of controlling exposure to NPs in a context of a major lack of specific data related to the toxicity of these substances and to the level of occupational exposure. The framework focuses on a structured approach dealing with hazard identification, exposure characterization, risk assessment and risk management. These are included in a prevention program that must be followed up, once it has been implemented, and refined through an iterative approach as new data become available.
机译：工程化纳米颗粒（NPS）是在研究实验室开发的，并在工业厂生产，其中可能发生最广泛的曝光。许多毒理学研究表明，与NPS的吸收有关的各种特定健康风险，但数据仍然有限，仍然存在许多不确定性。在质量基础上，NPS通常比尺寸更大的相同物质更大。这些颗粒显示尺寸依赖性不利生物效应，并且必须尽可能低地保持职业暴露。我们对职业环境的访问证明，许多工人不了解潜在的风险，在许多情况下，不执行适当的程序以限制职业暴露于这些产品。本文提出了职业风险管理框架，目的是控制在与这些物质的毒性有关的主要数据以及职业暴露的水平的情况下对NPS暴露的环境。该框架侧重于处理危险识别，曝光表征，风险评估和风险管理的结构化方法。这些包含在必须随访的预防计划中，一旦实施，并且通过迭代方法改进，因为新数据可用。

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