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首页> 外文会议>Nanoscience and Nanotechnology Symposium >Preparation of Silver-Chitosan Nanocomposites and Coating on Bandage for Antibacterial Wound Dressing Application
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Preparation of Silver-Chitosan Nanocomposites and Coating on Bandage for Antibacterial Wound Dressing Application

机译：抗菌伤口敷料应用中银壳聚糖纳米复合材料的制备

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Bandage is a medical device that is essential for wound dressing. To improve the performance of the bandage, it has been coated by silver-chitosan nanocomposites (Ag/Chit) with pad-dry-cure method. The nanocomposites were performed by chemical reduction method at room temperature using glucose as reducing agent, sodium hydroxide (NaOH) as accelerator reagent, silver nitrate (AgNO_3) as metal precursor and chitosan as stabilizing agent. Localized surface plasmon resonance (LSPR) absorption band of silver nanoparticles was investigated using UV-Vis spectrophotometer. The bandage coated Ag/Chit nanocomposites (B-Ag/Chit) were characterized by fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and scanning electron microscope (SEM). In addition, antibacterial activity of the bandage toward Gram positive (Staphylococcus aureus) and Gram negative (Escherichia coli) were also studied. The formation of silver nanoparticles was confirmed by the appearance of LSPR absorption peak at 412.2 - 423.2 nm. Coating of nanocomposite cause increasing rigidity of bandage and decreasing on crystallinity. The bandages of B-Ag/Chit demonstrated good activity against both Gram positive (S. aureus) and Gram negative (E.Coli). Thus the bandages have a potential to be used for antibacterial wound dressing application.
机译：绷带是一种对伤口敷料至关重要的医疗装置。为了提高绷带的性能，它已被银壳聚糖纳米复合材料（Ag / Chit）涂覆，具有垫 - 干固化方法。使用葡萄糖作为还原剂，氢氧化钠（NaOH）作为促进剂试剂，硝酸银（AgNO_3）作为金属前体和壳聚糖作为稳定剂，通过化学还原方法进行纳米复合材料。使用UV-Vis分光光度计研究了局部表面等离子体共振（LSPR）银纳米粒子的吸收带。通过傅里叶变换红外光谱（FTIR），X射线衍射（XRD）和扫描电子显微镜（SEM）表征绷带涂覆的Ag / Chit纳米复合材料（B-Ag / Chit）的特征。此外，还研究了刺刺刺（金黄色葡萄球菌）和克阴性（大肠杆菌）的粘结活性。通过在412.2-223.2nm处的LSPR吸收峰的外观确认银纳米颗粒的形成。纳米复合材料涂层导致绷带的刚性增加，结晶度降低。 B-Ag / Chit的绷带对克酸阳性（金黄色葡萄球菌）和革兰氏阴性（大肠杆菌）进行了良好的活性。因此，绷带具有用于抗菌伤口敷料应用的可能性。

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