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首页> 外文会议>International Conference on Practical Applications of Computational Biology Bioinformatics >Reconciliation of Regulatory Data: The Regulatory Networks of Escherichia coli and Bacillus subtilis
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Reconciliation of Regulatory Data: The Regulatory Networks of Escherichia coli and Bacillus subtilis

机译：监管数据的和解：大肠杆菌和枯草芽孢杆菌的监管网络

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摘要

Multiple efforts have been made to comprehend the regulatory machinery of model prokaryotic organisms, such as Escherichia coli and Bacillus subtilis. However, the lack of unification of published regulatory data reduces the potential of reconstructing whole genome transcriptional regulatory networks. The work hereby discussed, focuses on the retrieval and integration of relevant regulatory data from multiple resources, including databases, such as RegulonDB and DBTBS as well as available literature. This study presents state-of-art, reconciled transcriptional regulatory networks of the previously mentioned model organisms, as well as a topological and functional analysis.
机译：已经使多项努力理解模型原核生物的监管机制，例如大肠杆菌和枯草芽孢杆菌。 然而，公布的调节数据的统一缺乏统一减少了重建全基因组转录监管网络的可能性。 特此讨论的工作，侧重于检索和集成来自多个资源的相关法规数据，包括数据库，例如殿下和DBTB，以及可用文献。 本研究提出了先前提到的模型生物的最先进的，和解的转录调节网络，以及拓扑和功能分析。

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