• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>International Meeting of Advances in Thermofluids >Effects of Irregular Cerebrospinal Fluid Production Rate in Human Brain Ventricular System
【24h】

Effects of Irregular Cerebrospinal Fluid Production Rate in Human Brain Ventricular System

机译：不规则脑脊液生产率在人脑室系统中的影响

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Hydrocephalus is an abnormal accumulation of fluid in the ventricles and cavities in the brain. It occurs when the cerebrospinal fluid (CSF) flow or absorption is blocked or when excessive CSF is secreted. The excessive accumulation of CSF results in an abnormal widening of the ventricles. This widening creates potentially harmful pressure on the tissues of the brain. In this study, flow analysis of CSF was conducted on a three-dimensional model of the third ventricle and aqueduct of Sylvius, derived from MRI scans. CSF was modeled as Newtonian Fluid and its flow through the region of interest (ROI) was done using EFD.Lab software. Different steady flow rates through the Foramen of Monro, classified by normal and hydrocephalus cases, were modeled to investigate its effects. The results show that, for normal and hydrocephalus cases, the pressure drop of CSF flow across the third ventricle was observed to be linearly proportionally to the production rate increment. In conclusion, flow rates that cause pressure drop of 5 Pa was found to be the threshold for the initial sign of hydrocephalus.
机译：脑积水是脑内心室和脑腔中的液体异常积累。当脑脊髓液（CSF）流动或吸收被阻断或者当分泌过量的CSF时，发生。 CSF的过度积累导致心室的异常扩大。这种宽度会对大脑组织产生潜在的有害压力。在该研究中，CSF的流动分析在Sylvius的第三脑室和渡槽的三维模型中进行了来自MRI扫描的三维模型。 CSF以牛顿流体为模型，并通过efd.lab软件进行感兴趣区域（ROI）的流量。通过正常和脑积分案件分类的Monro孔子的不同稳定流速被建模，以调查其影响。结果表明，对于正常和脑积水病例，观察到第三脑室的CSF流量的压降是线性的与生产率增量线性成比例。总之，发现导致5Pa的压力下降的流速是脑积水初始迹象的阈值。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号