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Comparisons of Different Feature Sets for Predicting Carbohydrate-Binding Proteins From Amino Acid Sequences Using Support Vector Machine

机译:用载体载体机预测碳水化合物结合蛋白的不同特征集的比较

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Proteins which can interact with sugar chains but do not modify them are called as Carbohydrate-binding proteins. These proteins have several biological importance. To predict them computationally with SVM classifier, we have developed different feature sets-based on secondary structures and selective physicochemical properties of the constituent amino acids. The feature set formed with combination of both the secondary structures and physicochemical properties gives better prediction accuracy (up to 89.19 %). We have also prepared an up-to-date dataset of carbohydrate-binding proteins and non-carbohydrate-binding proteins in this work.
机译:可以与糖链相互作用但不改性它们的蛋白质称为碳水化合物结合蛋白。这些蛋白质有几种生物重要性。为了用SVM分类器计算它们,我们已经开发了不同的特征集 - 基于次要结构和组成氨基酸的选择性物理化学性质。具有二次结构和物理化学特性的组合形成的特征集可以提供更好的预测精度(高达89.19%)。我们还在本工作中制备了碳水化合物结合蛋白和非碳水化合物结合蛋白的最新数据集。

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