• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>World Asthma, Allergy COPD Forum >Different manner of subpopulations of neutrophils and monocytes - partners's myeloid phagocyte system , expressing the same membrane markers, in deep preterm newborns with congenital pneumonia
【24h】

Different manner of subpopulations of neutrophils and monocytes - partners's myeloid phagocyte system , expressing the same membrane markers, in deep preterm newborns with congenital pneumonia

机译：中性粒细胞和单核细胞的不同方式 - 伴侣的骨髓吞噬细胞系统，表达相同的膜标记，在深蓝的早熟新生儿与先天性肺炎

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The aim of our work was to identify and to compare the features simultaneous expression of the same surface membrane molecules of neutrophilic granulocytes (NG) in tandem with monocytes (MON ): CD64, CD32, CD16, CD11b. We had used flow cytometry with assessment of percent and absolute number of subpopulations MON and NG and the level of the density of expressed molecules by measure of the intensity of the fluorescence (MFI) in very preterm infants with congenital pneumonia in comparison with term healthy infants. In this study we had demostrated only CD64~+CD16~+CD32~+CD11b~+, CD64 CD16~+CD32~+CD11b~+ subpopulations of MON and NG at the full term newborns and the transformation of the phenotype of those subpopulations at deeply premature neonates with congenital pneumonia on the background of respiratory distress syndrome (RDS). The revealed features of quantitative and qualitative transformation described subpopulations of NG and MON of the studied patients were correlated with the severity of congenital pneumonia in deep premature newborns. At the same time our data demonstrated significant differences in the simultaneous expression of the same surface membrane molecules and remodeling phenotypes of NG in comparison with the same subpopulations MON. Thus we had indicated that there was severe dysfunction of both partners of MFS in deep preterm newborns with congenital pneumonia.
机译：我们的作品的目的是识别并比较与单核细胞（MON）：CD64，CD32，CD16，CD11b的同时表达相同表面膜分子（NG）的同一表面膜分子的特征表达。我们使用流式细胞术评估了百分比和NG的百分比和绝对数量，并且通过测量具有先天性肺炎的早产儿（MFI）的荧光（MFI）的强度与具有先天性肺炎的荧光（MFI）的强度进行了表达分子的密度水平。在这项研究中，我们脱染了CD64〜+ CD16〜+ CD32〜+ CD11b〜+，CD64 CD16〜+ CD32〜+ CD11b〜+亚叶，NM和NG的全术语新生儿和这些群体表型的转化对呼吸窘迫综合征（RDS）背景上的先天性肺炎的深过早新生儿。揭示的定量和定性转化的特征描述了NG和MON的亚群与学习患者的亚群与深过生的先天性新生儿的先天性肺炎的严重程度相关。同时，我们的数据在与同一亚群Mon的相比之下表现出同一表面膜分子的同时表达和Ng的重塑表型的显着差异。因此，我们表明，MFS的伴随着深入预存与先天性肺炎的伴侣伴有严重功能障碍。

著录项

相似文献

  • 外文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号