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Effect of specimen size on cancellous bone microstructural parameters

机译：试样大小对松质骨微结构参数的影响

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As the average life span of Japanese people continues to extend, the increasing incidence of osteoporosis within the aging society is becoming a major public health problem. Such diseases have a negative impact on Quality of Life and an urgent issue to find prevention and treatment methods. Currently, correlation between the microstructural parameters and the mechanical properties is shown by using an X-ray microtomography. In this study, the influence of the cancellous bone region on the correlation between the microstructural parameters, calculated by using X-ray microtomography images, and Young's modulus, which were obtained from the compression test, was clarified by targeting cancellous bone specimens of various regions, obtained from bovine femur. Cancellous bone specimens were obtained from the right femur of a bovine for the compression test. The correlation coefficient between Young's modulus and microstructural parameters was calculated. Cubic specimen in 5mm had the highest correlation coefficient between Young's modulus and microstructural parameters. Additionally, when specimen regions were 4 or 5mm, the standard deviation of each microstructural parameter had the smallest value, except for Trabecular Separation and Mean Intercept Length 3. The cancellous bone region of the cubic specimen in 5mm had a high correlation between microstructural parameters and Young's modulus and the value of the microstructural parameters of the small variation.
机译：随着日本人的平均寿命持续扩大，随着年迈的社会内骨质疏松症的发病率越来越大成为一个主要的公共卫生问题。这些疾病对生活质量产生负面影响和寻找预防和治疗方法的紧急问题。目前，通过使用X射线显微镜图显示微结构参数和机械性能之间的相关性。在该研究中，通过靶向各个区域的松质骨标本，阐明了通过使用X射线显微镜图像计算的微观结构参数与使用X射线显微镜图像计算的微观结构参数之间的相关性的影响。通过靶向各个区域的松质骨标本来阐明从压缩试验中获得的从牛股骨中获得。从牛牛股的牛牛芯获得压缩试验的松质骨标本。计算杨氏模量和微结构参数之间的相关系数。 5mm中的立方体标本在杨氏模量和微结构参数之间具有最高的相关系数。另外，当样品区域为4或5mm时​​，每个微观结构参数的标准偏差具有最小的值，除了小梁分离和平均截取长度3. 5mm中的立方标本的松质骨区在微结构参数之间具有高的相关性和杨氏模量和小变异的微观结构参数的值。

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