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首页> 外文会议>International Conference on Technologies and Materials for Renewable Energy, Environment and Sustainability >Increased Serum Interleukin-10 Could lead to Allergic Disease Development in Helicobacter pylori Infected Adult
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Increased Serum Interleukin-10 Could lead to Allergic Disease Development in Helicobacter pylori Infected Adult

机译：血清白细胞介素-10增加可能导致幽门螺杆菌感染成人的过敏性疾病发育

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Some research reported a protective effect of increased IL-10 in the development of allergic disease in children with H.pylori infection. Therefore this study aimed to investigate the possible protective effect of increased serum IL-10 levels and allergic disease symptoms in adult infected with H. pylori ,furthermore we studied an association between ABO blood group with H. pylori infection. Methodes: Slide heamagglutination test was used to determine the blood group phenotype in 214 patients seropositiveH.pylori which they submitted to Azadi teaching hospital in Kirkuk city-Iraq for diagnosis and treatment, in addition serum levels of anti H. pylori antibody,IL-10, IL-4 and total IgE were assayed using ELISA kits for 70 patients, as well as for 20 healthy control. Results. The result showed significant increasing of the serum levels IL-10 and IL-4(P=0.000,0.003 respectively) and total IgE level (p=0.014) in H. pylori seropositive patients. Also the study showed higher incidence of H.pylori infection within O blood group of patients in compared with general population (p=0.000). ConclusionH.pylori infection associated with increased IL-10 levels and IL-4 levels ,and IL-4 production may responsible for the increase in serum IgE level and higher incidence of infection in O blood phenotype may considered as an etiological risk factor for the development of H. pylori infection.
机译：一些研究报告了IL-10增加在H.Pylori感染儿童过敏性疾病中的保护作用。因此，本研究旨在调查血清IL-10水平和过敏性疾病症状在感染H. Pylori的可能性疾病症状的可能保护作用，此外我们研究了ABO血液组与H. Pylori感染之间的关联。方法：滑动铰孔凝集试验用于确定214名患者血清磷脂磷酸钠的血液组表型。它们在Kirkuk City-Iraq中的Azadi教学医院提交诊断和治疗，此外血清抗H.幽门螺杆菌抗体，IL-10使用ELISA试剂盒进行70名患者，以及20例健康对照，测定IL-4和总IgE。结果。结果表明，在幽门螺杆菌血清阳性患者中，血清IL-10和IL-10分别（P = 0.000.003分别）和总IgE水平（P = 0.014）的显着增加。此类研究表明，与一般人群相比，O血组患者患者内的H.Pylori感染发病率较高（P = 0.000）。与增加的IL-10水平和IL-4水平，和IL-4的产生相关联的ConclusionH.pylori感染可能负责在血清IgE水平的增加和感染的发生率较高的O型血液的表型可认为是用于发展的病因学危险因素H.幽门螺杆菌感染。

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