• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>American College of Veterinary SurgeonsACVS Surgery Summit >FELINE PAIN MANAGEMENT: ADAPTING YOUR APPROACH
【24h】

FELINE PAIN MANAGEMENT: ADAPTING YOUR APPROACH

机译：猫科动物疼痛管理：适应你的方法

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Designing an effective analgesic plan for the feline patient requires some thoughtful adaptation of the approach for the canine patient. Although generally the same classes of drugs may be used, differences in behavioral side effects, drug metabolismand underlying disease conditions must be taken into consideration. For example, a recent random selection of older feline patients found that 50% of them had some degree of chronic kidney disease (Marino et al, J Fel Med Surg, 2013). In addition, ease of drug administration may be of much greater importance than in the canine patient. Traditionally, the greatest barrier to effective pain management has been our inability to adequately assess pain in our feline patients. Cats generally do not vocalize the way many canine patients do when they are painful. Rather, a cat that is painful may sit in the back of the cage (if in a hospital environment), hide, act depressed, stop grooming, and become inappetent. At home, changes in activity may be difficult to monitor as some cats are generally more sedentary than others. More recently, feline specific pain assessment tools (e.g. feline specific acute pain scales) have been developed and are constantly being refined, improving our ability to make informed choices for our feline patients.Opioids are frequently used for pain control in veterinary medicine and are the mainstay of analgesic therapy in the perioperative period. Opioids act by binding to specific opioid receptors in the CNS (mu, kappa, delta) mimicking the effects of the endogenous opioids (endorphins, enkephalins, dynorphins). These receptors vary in their pharmacological effects (although all three produce analgesia) and their distribution throughout the body. Although opioids are grouped together according to their binding properties, their behavioral and physiological effects may be qualitatively quite different. Historically, pure opioid agonists (e.g. morphine, oxymorphone, methadone) were often avoided in feline patients due to fears of producing excitement (morphomania). However, recent studies have shown that opioids can be effectively used when appropriate doses (generally lower than those used in dogs) and recommended dosing intervals are used (Robertson and Taylor 2004). Hydromorphone may be more likely to be associated with pyrexia and other opioids may be preferred. In general, cardiovascular function is well maintained after opioid administration and less bradycardia is seen than in dogs.
机译：为猫科动物患者设计有效的镇痛计划需要对犬患者的方法进行一些深思熟虑的调整。虽然通常可以使用相同类别的药物，但必须考虑到行为副作用的差异，药物代谢和潜在的疾病条件。例如，最近的旧猫科动物患者的随机选择发现，其中50％具有一定程度的慢性肾病（Marino等，J Fel Med Surg，2013）。此外，易于药物管理可能比犬患者更重要。传统上，有效疼痛管理最大的障碍是我们无法充分评估猫科学患者的疼痛。猫通常不会发出许多犬患者的方式，当它们是痛苦的时候。相反，一只痛苦的猫可以坐在笼子的后面（如果在医院环境中），隐藏，行为郁闷，停止修饰，并变得厌倦。在家里，活动的变化可能难以监测，因为一些猫通常比其他猫更久坐。最近，猫类特异性疼痛评估工具（例如猫特异性急性疼痛尺度）已经开发并不断被改进，提高了我们对猫科学患者提供明智的选择的能力。蒸发体经常用于兽医中的疼痛控制，是围手术期镇痛治疗的主要疗法。阿片类药物通过与模拟内源性阿片类药物（内啡肽，Enkephalins，Dynorphins）的影响的CNS（穆，κ，Δ）中的特异性阿片受体结合。这些受体在其药理效应（尽管所有三种产生镇痛）和它们在整个身体中的分布时变化。虽然阿片类药物根据其结合特性进行分组，但它们的行为和生理效应可能是定性的。历史上，由于担心产生兴奋（混乱），养殖纯蛋白酶激动剂（例如吗啡，鼠话，美沙酮）通常在猫科动物中避免。然而，最近的研究表明，当适当的剂量（通常低于狗的那些）和推荐给药间隔时，可以有效地使用阿片类药物（Robertson和Taylor 2004）。液体白酮可能更可能与吡塞芽和其他阿片类药物相关。通常，在阿片类药物施用后保持心血管功能，并且比狗在狗中看到较少的心动过缓。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号