首页> 外文会议>Annual Meeting of The National Mastitis Council (U.S.). >Coagulase Negative Staphylococci Distribution in Dairy Herds with Automatic Milking System and Their Crosstalk with Staphylococcus aureus from Intramammary Infections and Teat Apex
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Coagulase Negative Staphylococci Distribution in Dairy Herds with Automatic Milking System and Their Crosstalk with Staphylococcus aureus from Intramammary Infections and Teat Apex

机译:凝固酶阴性葡萄球菌分布在乳制品牛群中,自动挤奶系统及其串扰于脑内感染和奶嘴的金黄色葡萄球菌

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Management of udder health in automatic milking systems (AMS) differs from conventional milking systems. Dairy cows in AMS can be milked up to five times daily without any human contact with the udder. The longer milking duration may cause higher riskof cows acquiring new intramammary infections (IMI) with CNS . Additionally, the frequent exposure of the teat skin to disinfectants may affect the teat apex microbiota. Epidemiological characteristics of CNS are available from numerous studies in conventional milking systems but knowledge about CNS-characteristics is sparse for AMS herds. Therefore, understanding the distribution patterns of habitat-specific CNS species could improve the udder health management in AMS herds. The role of CNS on the risk to acquire of IMI with Staphylococcus aureus (S. aureus) is poorly understood. The quorum-sensing accessory gene regulator {agf) system of S. aureus plays a central role in its pathogenesis and virulence (Singh and Ray, 2014). In the human medicine domain, some staphylococcal species (e.g., & epidermidis) produce auto-inducing peptide (AIP)-like molecules, which inhibit S. aureus agr and toxin production (Otto et al., 2001). The objectives of this study were to 1) investigate the distribution of CNS species from aseptically collected quarter-milk samples and teat skin in dairy herds with AMS, and 2) examine if the isolated CNS influence the expression of S. aureus virulence factors controlled by the agr quorum sensing system.
机译:自动挤奶系统(AMS)中的乳房健康管理与传统的挤奶系统不同。 AMS中的乳制品奶牛可以每天挤奶多达五次,没有任何与乳房接触的人。挤奶持续时间越长可能导致牛的牛奶率较高,以CNS获取新的内部感染(IMI)。另外,乳酸皮肤频繁暴露于消毒剂可能会影响乳头薄膜微生物。 CNS的流行病学特征可从常规挤奶系统中的众多研究中获得,但是关于CNS特征的知识对于AMS群体稀疏。因此,了解栖息地特异性CNS种类的分布模式可以改善AMS牛群中的乳房健康管理。 CNS对含有金黄色葡萄球菌(金黄色葡萄球菌)获得IMI的风险的作用很差。 S.金黄色葡萄球菌的仲裁辅助基因调节剂{agf)体系在其发病机制和毒力(Singh和Ray,2014)中起着核心作用。在人类药物结构域中,一些葡萄球菌(例如,&ePIDermidis)产生自身诱导的肽(AIP) - 样子分子,其抑制了金黄色葡萄球菌和毒素生产(Otto等,2001)。本研究的目标是1)调查CNS种类从无菌收集的四分之一牛奶样品和乳酸牛群中的乳酸皮肤分布,2)检查孤立的CNS是否影响了由此控制的S.UUREUS毒力因子的表达农业法定传感系统。

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