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Five Points to Revise the Five-Point Mastitis Control Plan

机译:五点修订五点乳腺炎控制计划

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Mastitis is one of the most prevalent and costly diseases afflicting dairy farms worldwide (Steeneveld et al., 2011). Financial losses associated with mastitis are attributed to decreased milk production and quality, increased culling rates, discardedmilk, treatment costs, and adverse effects on fertility and early pregnancy (Hertl et al., 2014). The greatest incidence of mastitis occurs within the first weeks following parturition that overlaps with the transition period (Schukken et al., 2011), atime of negative energy balance following the onset of lactation and a change in immune bias from Th2-dominated immune responsiveness in late gestation to Thl domination in early lactation (Quesnell et al., 2012). Bovine mastitis is most commonly causedby bacterial intramammary infections (IMF). A large number of bacterial pathogens have been associated with bovine IMI (Hertl et al., 2014; Cha et al., 2016). In this presentation, 5 new developments in bovine udder health will be highlighted. These developments include the increased knowledge of the normal and abnormal intramammary microbiome of the bovine mammary gland, the increased understanding of the immune-biology of the mammary gland, particularly during late gestation and early lactation, and finally the changing perspectives on antimicrobial use during the dry period of dairy cows.
机译:乳腺炎是全球乳房农场的最普遍和昂贵的疾病之一(Steeneveld等,2011)。与乳腺炎有关的财务损失归因于牛奶产量和质量下降,增加剔除率,丢弃率,治疗成本以及对生育和早期的不利影响(Hertl等,2014)。在分娩后的第一周内发生最大的乳腺炎发生率(Schukken等,2011),在哺乳期发作后,负能量平衡的原子和免疫偏见的变化,来自Th2主导的免疫反应性在早期哺乳期统治的后期妊娠(Quesnell等,2012)。牛乳腺炎是最常见的细菌内型感染(IMF)。大量的细菌病原体已与牛IMI(Hertl等,2014; Cha等,2016)有关。在本演示文献中,将突出5个牛乳房健康的新发展。这些发展包括牛乳腺的正常和异常胎儿微生物组的知识,增加了对乳腺免疫生物学的了解,特别是在晚期妊娠和早期哺乳期间,最后改变了在抗微生物用途的视角干燥时期的奶牛。

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