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首页> 外文会议>International Pharmacy Conference >The efficacy of black cumin seed {Nigella sativa) oil and hypoglycemic drug combination to reduce HbAlc level in patients with metabolic syndrome risk
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The efficacy of black cumin seed {Nigella sativa) oil and hypoglycemic drug combination to reduce HbAlc level in patients with metabolic syndrome risk

机译：黑孜然种子{Nigella Sativa）油和降血糖药物组合的疗效减少了代谢综合征风险患者的HBALC水平

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Metabolic syndrome is a conditions causgd by metabolic abnormalities include central obesity, atherogenic dyslipidemia, hypertension, and insulin resistance. HbAlc examination is required to study the long-term glycemic status and to prevent diabetic complications of metabolic syndrome. The purpose of this study is to determine the efficacy of black cumin seed (Nigella sativa) oil and hypoglycemic drug combination to reduce HbAlc level in patients with metabolic syndrome risk. This research performed using an experimental randomized single - blind controlled trial design. A total of 99 outpatients at the Jetis I Public Health Center, Yogyakarta, Indonesia with metabolic syndrome risk were divided into three groups: The control group received placebo and two treatment groups received black seed oil orally at dose of 1.5 mL/day and 3 mL/day, respectively, for 20 days. The clinical conditions such as blood pressure, pulse rate, BMI, blood glucose serum and HbAlc levels were examined on day 0 and 21. The results obtained were analyzed with one-way ANOVA test. The mean of HbAlc levels of all groups before treatment was higher than the normal values and there was no significant difference in HbAlc value on day 0. Administration of 1.5 and 3 mL/day of black seed oil for 20 days decreased (p<0.05) HbAlc levels. It can be concluded that administration of black cumin seed oil and hypoglycemic drug combination for 20 days in patients at risk of metabolic syndrome may reduce to HbAlc levels.
机译：代谢综合征是代谢异常的成因的条件包括中央肥胖，血液发生血脂血症，高血压和胰岛素抵抗力。需要HBALC检查来研究长期血糖状态，并防止代谢综合征的糖尿病并发症。本研究的目的是确定黑色孜然种子（Nigella sativa）油和降血糖药物组合减少代谢综合征风险患者的HBALC水平的疗效。该研究采用实验性随机单盲对照试验设计进行。在捷思我公共卫生中心，日惹，印度尼西亚共有99名门诊患者分为三组：对照组接受安慰剂和两种治疗组在1.5毫升/天的剂量口服，3毫升接受黑色种子油/天，分别为20天。在第0天和第21天检查血压，脉搏率，BMI，血糖血清和HBALC水平等临床条件。用单向ANOVA试验分析所得结果。治疗前所有组的HBALC水平的平均值高于正常值，第0天的HBALC值没有显着差异。施用1.5和3毫升/天的黑色种子油减少（P <0.05） HBALC水平。可以得出结论，在代谢综合征风险的患者中施用黑孜然种子油和低血糖药物组合的给药可能降低到HBALC水平。

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