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HbA1c as Glycemic Control is Associated with Triglycerides Levels in Type 2 Diabetes Mellitus

机译:作为血糖对照的HBA1C与2型糖尿病的甘油三酯水平相关

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Based on WHO data in 2017, around 150 million people suffer from diabetes mellitus worldwide and it is estimated that this number can double by 2025. Most of this increase will occur in developing countries due to population growth, aging, unhealthy diets, obesity and sedentary lifestyle. Type 2 Diabetes Mellitus (DM) is a metabolic disorder that is marked by the rise in blood sugar due to a decrease in insulin secretion by pancreatic beta cells. The causes of microvascular and macrovascular complications in DM are chronic hyperglycemia that is measured by Hemoglobin A1c (HbA1c) as a control, and the risk factors to be proven, namely serum lipid levels, especially triglycerides which increase in dyslipidemia. Therefore hyperglycemia and dyslipidemia should be reduced, so that the number of microvascular and macrovascular complications in DM patients can be slowed down. The purpose of this study is to measure HbA1c as glycemic control were associated with triglycerides levels in type 2 DM. The method used was cross sectional design conducted by taking 90 data patients who performed HbA1c and triglycerides concurrently at Tarakan Hospital in Central Jakarta in 2017. It was found in 80 patients (88.9%) with age above 45 years, the average HbA1c level was 8% which showed poor control and the mean level of triglycerides above the reference was 170 mg/dL. An increase in triglyceride levels as well as an increase in HbA1c levels is a poor indicator of glycemic control. Based on the results of statistical tests, there was a significant correlation (p value = 0,000) between HbA1c and triglycerides with a positive correlation direction (r = 0,594). It can be concluded, the worse the HbA1c control, the higher triglyceride levels in the blood so that patients with diabetes mellitus must carry out glycemic control regularly to prevent complications.
机译:基于2017年的世卫组织,大约1.5亿人患有全球糖尿病糖尿病,据估计,这一数字可以平二到2025年。由于人口增长,老龄化,不健康的饮食,肥胖和久坐的,发展中国家的大多数增加都会发生这种增加生活方式。 2型糖尿病(DM)是一种代谢紊乱,其由于胰岛素β细胞的胰岛素分泌而导致的血糖升高。 DM中微血管和大血管并发症的原因是慢性高血糖,其通过血红蛋白A1C(HBA1C)作为对照来测量,以及所经验证明的危险因素,即血清脂质水平,尤其是血脂血症增加的甘油三酯。因此,应减少高血糖和血脂血症,使DM患者的微血管和大血管并发症的数量减慢。本研究的目的是测量HBA1C,因为血糖对照与2 DM型甘油三酯水平相关。使用的方法是通过服用90例数据患者在2017年在雅加达中部塔拉坎医院进行HBA1C和甘油三酯进行的90例数据患者进行的横截面设计。它已在80岁患者(88.9%)以上,年龄超过45岁,平均HBA1C水平为8表现出差和上述甘油三酯的平均水平的%为170mg / dL。甘油三酯水平的增加以及HBA1C水平的增加是血糖控制的差。基于统计测试的结果,HBA1C和甘油三酯之间存在显着的相关性(P值= 0,000),其具有正相关方向(R = 0.594)。可以得出结论,HBA1C控制较差,血液中甘油三酯水平较高,使糖尿病患者必须定期进行血糖控制以防止并发症。

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