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首页> 外文会议>International Conference on Materials Engineering and Science >Synthesis, characterization and study the physical properties of new 1, 2, 4-Triazoles Mannich-Base derivatives
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Synthesis, characterization and study the physical properties of new 1, 2, 4-Triazoles Mannich-Base derivatives

机译：新增1,2,4-Tri唑的物理性质的合成，表征和研究Mannich基础衍生物的物理性质

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摘要

In the present study, novel derivatives of 1,2,4-Triazoles were synthesised using optimized chemical reaction methods,l-((4-(5-(prop-2-yn-l-ylthio)-4H-l,2,4-triazol-3-yl) phenyl) diazenyl) naphthalen-2-ol [M] was used as starting material to prepare compounds [M1-M6] via reaction of [M] with different amino drugs [ciprofloxacin, paracetemole, pseuphedrine, theophylline, chlorodizepoxide and sulphadiazine], reaction with formaldehyde and secondary amines afforded the Mannich bases. The UV-Vis spectra of prepared compounds displayed broad CT bands with end absorptions reaching closely into the near infrared reflecting the effective of conjugation. Also, displayed that drug group plays an important role in modulating the fluorescence properties of [M]. The synthesized derivatives were characterized by TLC, FTIR, Uv-Visible, fluorescence and 1~H,(13)~CNMR techniques for their structural confirmation.
机译：在本研究中，使用优化的化学反应方法，L - （（4-（5-（PROP-2-YN-L-YLTHIO）-4H-L，2，2，2，1,2,4-1，2，合成1,2,4-三唑的新衍生物。 4-三唑-3-基）苯基）二亚苯基）萘基-2-醇[M]用作原料，通过[M]用不同氨基药物的反应制备化合物[M1-M6] [Ciprofloxacin，髌果酰醇，副酚，副酚，副嘧啶，茶碱，氯己酮和硫代噻嗪]，与甲醛和仲胺的反应得到了曼尼希碱。制备的化合物的UV-Vis光谱显示出宽的CT带，其最终吸收与反射缀合的有效的近红外线达到近的近红外线。此外，展示药物组在调节[M]的荧光性质方面发挥着重要作用。合成衍生物的特征在于TLC，FTIR，UV可见，荧光和1〜H，（13）〜CNMR技术，用于其结构确认。

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