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Hybrid photodetector for single-molecule spectroscopy and microscopy

机译:用于单分子光谱和显微镜的混合光电探测器

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We report benchmark tests of a new single-photon counting detector based on a GaAsP photocathode and an electron-bombarded avalanche photodiode developed by Hamamatsu Photonics. We compare its performance with those of standard Geiger-mode avalanche photodiodes. We show its advantages for FCS due to the absence of after-pulsing and for fluorescence lifetime measurements due to its excellent time resolution. Its large sensitive area also greatly simplifies setup alignment. Its spectral sensitivity being similar to that of recently introduced CMOS SPADs, this new detector could become a valuable tool for single-molecule fluorescence measurements, as well as for many other applications.
机译:我们报告基于GaASP光电阴极的新型单光子计数检测器的基准测试和由Hamamatsu Photonics开发的电子轰击的雪崩光电二极管。我们将其性能与标准的地革命模式雪崩光电二极管进行比较。由于由于其优异的时间分辨率,因此由于不存在后脉冲和荧光寿命测量而导致FCS的优点。它的大敏感区域也大大简化了设置对齐。其光谱敏感性与最近介绍的CMOS Spad相似,这种新探测器可能成为单分子荧光测量的有价值的工具,以及许多其他应用。

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