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Major Depressive Episode and Perimenopause

机译:主要抑郁症和周刊

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Purpose: To assess the clinical manifestations of perimenopause linked to depression. Introduction: It is well known that major depressive episode occurs more frequently in women addressing medical consultation for symptoms regarding the perimenopause. This is because menopause comes with a high risk of affective disorders. Mood disturbances are present in about 50% of the patients addressing the gynaecologist. Material and Methods: 80 women, aged 45 to 55 years, were divided into two groups: one consisting of patients diagnosed with major depressive episode from the District General Hospital of Huedin and the 2nd Psychiatric Clinic, Cluj-Napoca and the other of healthy women. The psychometric instruments used were Hamilton Depression Rating Scale, the Perz list of menopausal symptoms and Sloan scale for frequency and severity of hot flashes. Psychiatric symptoms of menopause and those of major depressive episode can be taken one for the other. To prevent that, we focused only on somatic vasomotor symptoms. The assessments were carried out at set intervals of time. The data was statistical analyzed. Results and Discussion: The given results indicate that depression in menopause is well associated with the frequency of hot flashes (r = 0.722; p = .000), the severity of hot flashes (r = 0.769; p = .000), the frequency of menopausal vasomotor symptoms (r = 0.721; p = .000), the severity of menopausal vasomotor symptoms (r = 0.754; p = .000) and with the premenstrual dysphoric syndrome (r = 0.795; p = .000). Another association was noted between the premenstrual dysphoric syndrome and the frequency of the vasomotor symptoms (r = 0.672; p = .000) and with the severity of vasomotor symptoms (r = 0.673; p = .000) as well. Conclusion: The severity of the depression may be influenced by the severity and frequency of menopausal symptoms and by the presence of the premenstrual dysphoric syndrome. The risk of major depressive episode may increase during perimenopause.
机译:目的:评估围绕抑郁症的临床表现。介绍:众所周知,主要抑郁发作在寻求关于围绕围本症状的症状的妇女中更频繁地发生。这是因为更年期具有高风险的情感障碍。在解决妇科医生的患者的约50%中存在情绪紊乱。材料和方法:80岁的女性,年龄45至55岁,分为两组:一个组成的患者,患者被诊断出从Huedin和第2个精神科诊所,Cluj-Napoca和其他健康女性的综合院长的主要抑郁症。所使用的心理测量仪器是汉密尔顿抑郁率评级,凡尔斯绝经症状列表和斯隆的频率和炎热闪光的严重程度。绝经的精神症状和主要抑郁发作的症状可以为另一个。为了防止,我们只关注体细胞激素症状。评估以设定的时间间隔进行。数据进行了统计分析。结果与讨论:给定结果表明更年期的抑郁症与热闪光频率良好相关(r = 0.722; p = .000),热闪光的严重程度(r = 0.769; p = .000),频率更年期血管运动症状(r = 0.721; p = .000),更年期血管运动症状的严重程度(r = 0.754; p = .000),并且具有初步缺血综合征(r = 0.795; p = .000)。在经常疑风综合征和血管振动症症状的频率之间(r = 0.672; p = .000)和血管传道症状的严重程度以及血管运动症状(r = 0.673; p = .000)之间的另一个关联。结论:抑郁症的严重程度可能受绝经症状的严重程度和频率的影响,并通过过早的疑似综合征存在。在围绝经期期间,主要抑郁发作的风险可能会增加。

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