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Effect of Flavonoid Quercetin on Reversal of TGF-Beta-Induced Epithelial to Mesenchymal Transition in Prostate Cancer (PC-3) CellLine

机译：类黄酮槲皮素对前列腺癌（PC-3）细胞线中TGF-β诱导的TGF-Beta诱导的下皮逆转的影响

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Transforming growth factor-beta (TGF-beta) induces EMT in epithelial cells and is necessary for acquisition of invasive phenotype in Prostate cancer. It has been hypothesized that prostate cells adopt embryonic signaling pathways (such as Wnt) that are generally silent. The purpose of this study was to evaluate the effect of flavonoid Quercetin on TGF-beta-induced EMT in Prostate cancer (PC-3) cell line. In the present study in silico analysis of various pathways involved in Prostate cancer was carried out which led to the identification of Wnt signaling pathway as the most significantly affected pathway.

机译：转化生长因子-β（TGF-β）诱导上皮细胞中的EMT，并且是在前列腺癌中获取侵袭性表型所必需的。已经假设前列腺细胞采用通常沉默的胚胎信号通路（如WNT）。本研究的目的是评估黄酮类槲皮素对前列腺癌（PC-3）细胞系中TGF-Beta诱导的EMT的影响。在本研究中，进行了涉及前列腺癌的各种途径的硅分析，其导致WNT信号通路作为最显着影响的途径。

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《International Molecular Medicine Tri-Conference.》|2016年|1 CD-ROM ;|共1页
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Meghna Baruah; Neeti Shartna; An P. Khwekar;
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1. Quercetin reverses EGF-induced epithelial to mesenchymal transition and invasiveness in prostate cancer (PC-3) cell line via EGFR/PI3K/Akt pathway [J] . Bhat Firdous Ahmad, Sharmila G., Balakrishnan S., The Journal of Nutritional Biochemistry . 2014,第11期

机译：槲皮素通过EGFR / PI3K / Akt通路逆转EGF诱导的前列腺癌（PC-3）细胞系上皮细胞向间质转化和侵袭性
2. Effects of dietary flavonoids, luteolin, and quercetin on the reversal of epithelial-mesenchymal transition in A431 epidermal cancer cells. [J] . Lin YS, Tsai PH, Kandaswami CC, Cancer science. . 2011,第10期

机译：膳食类黄酮，木犀草素和槲皮素对A431表皮癌细胞上皮间质转化逆转的影响。
3. Effects of dietary flavonoids, luteolin, and quercetin on the reversal of epithelial–mesenchymal transition in A431 epidermal cancer cells [J] . Chia-Hsiung Cheng, Chithan C. Kandaswami, Ferng-Chun Ke, Cancer science. . 2011,第10期

机译：膳食类黄酮，木犀草素和槲皮素对A431表皮癌细胞上皮间质转化逆转的影响
4. Effect of Flavonoid Quercetin on Reversal of TGF-Beta-Induced Epithelial to Mesenchymal Transition in Prostate Cancer (PC-3) CellLine [C] . Meghna Baruah, Neeti Shartna, An P. Khwekar International Molecular Medicine Tri-Conference. . 2016

机译：类黄酮槲皮素对前列腺癌（PC-3）细胞线中TGF-β诱导的TGF-Beta诱导的下皮逆转的影响
5. gamma-Tocotrienol Reversal of Epithelial-to-Mesenchymal Transition in Breast Cancer Cells [D] . Ahmed, Rayan Abdulbasit. 2018

机译：γ-生育三烯酚逆转的乳腺癌细胞上皮向间充质转变。
6. Effect of SIRT1 Gene on Epithelial-Mesenchymal Transition of Human Prostate Cancer PC-3 Cells [O] . Ying Cui, Jiang Li, Fei Zheng, 2016

机译：SIRT1基因对人前列腺癌PC-3细胞上皮-间质转化的影响
7. Effects of dietary flavonoids, luteolin, and quercetin on the reversal of epithelial-mesenchymal transition in A431 epidermal cancer cells [O] . Yung-Sheng Lin, Pei-Hsun Tsai, Chithan C. Kandaswami, 2011

机译：膳食黄酮，叶黄素和槲皮素对A431表皮癌细胞上皮 - 间充质转换逆转的影响

Effect of Flavonoid Quercetin on Reversal of TGF-Beta-Induced Epithelial to Mesenchymal Transition in Prostate Cancer (PC-3) CellLine

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