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Effectiveness of marine fungal symbiont isolated from soft coral Sinularia sp. from Panjang Island as antifungal

机译:海洋真菌Symbiont软珊瑚Sinularia SP的有效性。 从磐安岛作为抗真菌

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Soft corals are invertebrates living on coral reefs that produce bioactive compound that can be used such as an antibacterial, antifungal, anti-tumor,and anti iriflamantory that are beneficial for the pharmaceutical industry. Several studies have shown that fungi are very rich of natural chemical compounds that are potential as a source of new drugs, but there is few research in marine fungal symbionts. In this research we collecteda soft coralSinularia sp. as source of marine fungal symbionts from Panjang island of the North Java Sea,A total ofl5 fungi were successfully isolated and screened usingoverlay method against pathogenic fungiCandida Albicans and Aspergillus flavus.The results revealed that a fungalsymbiont was able to inhibit the growth of pathogenic fungi. Phytochemical tests showed that phenolic, triterpenoid and flavanoid compounds were detected within fungal extract. Molecular identification based on 18s rRNA gene showed that the active fungal was closely related to Aspergillus unguis.
机译:软珊瑚是无脊椎动物,生活在珊瑚礁上,产生可以使用的生物活性化合物,例如抗菌,抗真菌,抗肿瘤和抗Iriflamantory,这些是有益的制药行业。几项研究表明,真菌是非常丰富的天然化学化合物,这是新药来源的潜在潜力,但在海洋真菌共生的研究中很少。在这项研究中,我们收集了Soft Coralsinularia sp。作为北爪哇岛蒲大青岛的海洋真菌共生源来源,总共综合分离出来,筛选了促进致病性真菌和毒素的overoverlay方法和曲霉属植物。结果表明,一种菌酸酵母能够抑制致病性真菌的生长。植物化学测试表明,在真菌提取物中检测到酚醛,三萜类化合物和黄烷化合物。基于18S rRNA基因的分子鉴定表明,活性真菌与Aspergillus Unguis密切相关。

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