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BRIEF COMMUNICATION: Does Viagra protect fetal lambs against maternal pregnancy toxaemia?

机译:简要沟通:伟哥是否会保护胎儿羊羔对母亲妊娠毒素吗?

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Poor fetal growth is commonly caused by placental insufficiency. In sheep, multiple fetuses have relatively small placentae with fewer cotyledons than singletons, limiting blood flow to the placenta, especially in late gestation when fetal growth rateis highest. Factors that reduce fetal growth, such as maternal genotype, nutrition, age, parity, fetal number, or environmental temperature, typically reduce placental size and are associated with lower rates of fetal oxygen and nutrient uptakes and placental blood flow (Reynolds & Redmer 2001). Further, circumstances that influence placental vascular development have a dramatic impact on fetal growth and development, and affect neonatal survival and growth (Borowicz et al. 2007; Satterfield et al, 2010).
机译:胎儿生长不良通常是由胎盘不足引起的。在绵羊中,多个胎儿具有比单身的胎儿相对小的胎盘,而不是单身,限制血液流向胎盘,特别是在胎儿生长率最高的时候妊娠期妊娠。减少胎儿生长的因素,例如母体基因型,营养,年龄,奇偶校验,胎儿数或环境温度,通常会降低胎盘尺寸,并且与胎儿氧气和营养增高速和胎盘血流的较低速率相关(Reynolds&Redmer 2001) 。此外,影响胎盘血管发育的情况对胎儿生长和发育产生了显着影响,并影响新生儿生存和生长(Borowicz等,2007; Satterfield等,2010)。

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