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Isolation and Antibacterial Activity Test of Lauric Acid from Crude Coconut Oil (Cocos nucifera L.)

机译:粗椰子油(Cocos Nucifera L)的月桂酸分离和抗菌活性试验

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Isolation of lauric acid from crude coconut oil (CCO) has been done. Neutralization of CCO using 30% Na_2CO_3 solution could decrease its acid value from 1.69 to 0.48. Transesterification reactions of neutral coconut oil with methanol and K_2CO_3 at 55°C in 3 hours produced methyl laurate in 52% purity. Methyl laurate with 87% purity could be isolated by fractionatal distillation at 130-140°C. Hydrolysis of methyl laurate with NaOH produced solid lauric acidin 84% yield. Lauric acid at 5% concentration could inhibit the growth of all bacteria tested but it is still lower than Ciprofloxacin.
机译:已经完成了来自粗椰子油(CCO)的月桂酸的分离。使用30%Na_2CO_3溶液中和CCO可以将其酸值从1.69降至0.48。中性椰子油与甲醇和K_2CO_3在3小时内的甲醇和K_2CO_3的酯交换反应在52%纯度中产生甲基。通过在130-140℃下通过部分蒸馏来分离87%纯度的甲基甲基。用NaOH生产的固体月桂酸盐的甲基水解84%产率。 5%浓度的月桂酸可以抑制所测试的所有细菌的生长,但它仍然低于环丙沙星。

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