Objective: The purpose of this study was to describe changes in serum Cholesterol following Caloric Restriction (CR) intervention plus swimming training. Methods: Eight-week-old male Wistar rats were randomly divided into six groups: normal control (NC) group, 60 minutes of swimming (S) exercise group, 20% caloric restriction, 40% caloric restriction, 20% caloric restriction, and 60 minutes of swimming exercise group and 40% caloric restriction and 60 minutes of swimming exercise group. After 12 weeks, the serums Cholesterol were measured in rats. Results: When compared with the NC group, TG was lower significantly in S group, and HDL was higher significantly, and the rats in both 20%CR-S group and 40%CR-S had lower level of TG, and higher HDL. However, only TC in 20%CR-S group was lower. Both in 20% CR group and 40% CR group, TG were lower than in NC group, and HDL was higher. HDL was higher in 20%CR group than 40% CR group. Conclusions: The chronic exercise was able to reduce the level of TC, TG, and LDL, and elevate high-density lipoprotein. CR alone could reduce hyperlipidemia of animals, and swimming exercise could induce elevated HDL. Additionally, the results also reinforce the idea that a combination of both strategies is better than either individually for combating hyperlipidemia.
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