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Effect of plant polyphenols as antioxidant alternatives to vitamin E in diets offered to pigs

机译:植物多酚作为维生素E饮食中的抗氧化剂替代品的影响

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Oxidative stress is the product of an imbalance between free radicals and antioxidants that can damage cell components, and is associated with compromised growth, disease, and the ageing process.1 However, free radicals can also serve a regulatory role in metabolism (e.g., free radicals participate in induction of hyper-activated sperm motility and acrosome reaction).1 Vitamin E is a key antioxidant, and is typically dosed well above NRC requirements3 to reduce half-life of free radicals.4 However, overdosing antioxidants may also impede regulatory processes dependent on free radicals. A more balanced antioxidant approach should be favored: rather than adding one antioxidant at a very high level, dosing a range of molecules with antioxidant properties but with different radical affinities and different distributions in the body. This allows the body to better control the antioxidant defenses without impeding the regulatory actions of tree radicals. Plant polyphenols possess the same radical-quenching basic structure as vitamin E, and may complement the antioxidant defense of the animal. Two research trials were conducted to determine the effect of vitamin E in combination with a polyphenol blend vs. a high dose of only vitamin E on oxidative stress and performance of pigs.
机译:氧化应激是可损害细胞组分的自由基和抗氧化剂之间的不平衡的产物,并且与受损的生长,疾病和衰老过程有关。然而,自由基也可以用于代谢中的调节作用(例如,自由基团参与诱导超激活的精子运动和取物反应).1维生素E是一个关键的抗氧化剂,并且通常在NRC要求中呈现良好的抗氧化剂3以减少自由基的半衰期。然而,过量的抗氧化剂也可能阻碍调节过程依赖于自由基。应该有利于更平衡的抗氧化方法:而不是在非常高的水平下加入一个抗氧化剂,给予一系列具有抗氧化剂性质的分子,但具有不同的自由基亲缘性和身体的不同分布。这使身体能够更好地控制抗氧化剂防御,而不会阻碍树自由基的调节作用。植物多酚具有与维生素E相同的自由基淬火基本结构,并且可以补充动物的抗氧化防御。进行了两种研究试验以确定维生素E与多酚混合物与多剂量维生​​素E组合的影响氧化应激和猪的性能。

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