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Effect of Low Frequency Repetitive Transcranial Magnetic Stimulation Treatment on Non-Suicidal Self-Injury Behaviour and Intention of Depressed Adolescents

机译:低频重复经颅磁刺激治疗对抑制青少年非自杀自损伤的影响

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Background: Non-suicidal self-injury behaviours have been commonly observed among adolescents. At the same time, recent studies suggested that depression might be an independent risk factor for non-suicidal self-injury behaviours. Objectives: This study aimed to explore the efficacy of a two weeks course of repetitive transcranial magnetic stimulation (rTMS) treatment on adolescent patients of depression disorder, to relive their depressive symptoms, and reduce non-suicidal self-injury (NSSI) behaviours and intentions within the patients. Method: Within randomized single-blinded trails, 55 adolescent patients of depression disorder with a mean age of 16.75 years (n=55, SD=2.51, range=13-22) were assessed using 24-iterm Hamilton Depression Rating Scale (HDRS), Self-rating depression scale (SDS) and Adolescent Non-suicidal Self-injury Assessment Questionnaire (ANSSIQ) before and after treatment. The patients were divided into four group: Medicated true-Stimulation group, Medicated sham-stimulation group, None-medicated true-stimulation group and None-medicated sham-stimulation group. The statistic of t-tests were used to compare pre/post scores of factors on HDRS, SDS, ANSSIQ. Result: The data shows that after two weeks of rTMS treatment, the depression symptoms of adolescent patients can be relieved. And this treatment has a major effect on reducing the risk of self-injury. Conclusion: rTMS treatment can significantly relive the clinical symptoms of adolescents with depression, and also have a certain inhibitory effect on adolescent non-suicidal self-injury behaviour and intention.
机译:背景:青少年中通常观察到非自杀性自伤行为。与此同时,最近的研究表明,抑郁症可能是非自杀自我伤害行为的独立危险因素。目的:本研究旨在探讨两周的重复经颅磁刺激(RTMS)治疗对青少年抑郁症患者的疗效,以重温抑郁症状,减少非自杀性自我损伤(NSSI)行为和意图在患者内。方法:使用24-ITERM Hamilton抑郁率秤(HDR)评估55例抑郁症抑郁症的青少年抑郁症患者的抑郁症患者(n = 55,sd = 2.51,范围= 13-22) ,自评抑郁尺度(SDS)和青少年非自杀自我伤害评估问卷(ANSSIQ)治疗前后。患者分为四组:药物真正刺激组,药物假刺激组,无药物真正刺激组和无药物假刺激组。 T-Tests的统计数据用于比较HDRS,SDS,ANSSIQ的预/柱分数。结果:数据显示,经过两周的rtms治疗后,可以放松青少年患者的抑郁症状。这种治疗对降低自我伤害风险产生重大影响。结论:RTMS治疗可显着重温抑郁症的青少年的临床症状,对青少年非自杀自损伤行为和意图具有一定的抑制作用。

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