Pharmacokinetics evaluation of soft agglomerates containing enteric pantoprazole-loaded microparticles in dogs

机译：药代动力学评估含有肠道泮托唑加载的微粒的软凝聚物在狗中的微粒

获取原文

页面导航

摘要
著录项
相似文献
相关主题

摘要

Soft agglomerates prepared with pantoprazole-loaded microparticles and a spray-dried powder of mannitol and lecithin were evaluated for their pharmacokinetics in dogs after oral administration. Soft agglomerates presented slightly higher bioavailability than the reference enteric coated tablet and significantly lower lag-time of absorption.

机译：用泮托拉唑加载的微粒制备的软聚物和甘露醇和卵磷脂的喷雾干燥粉末在口服给药后的药代动力学中评估其药代动力学。软凝聚物的生物利用度略高于参考肠溶包衣片，并显着降低吸收滞后时间。

著录项

来源
《Annual meeting exposition of the Controlled Release Society》|2009年||共2页
会议地点
作者

展开▼
作者单位

展开▼
会议组织
原文格式 PDF
正文语种
中图分类药学;
关键词

相似文献

外文文献
中文文献
专利

1. Pharmacokinetics evaluation of soft agglomerates for prompt delivery of enteric pantoprazole-loaded microparticles. [J] . Raffin RP, Colome LM, Hoffmeister CR, European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2010,第2期

机译：软团聚体的药代动力学评估，可快速递送肠溶性azole托拉唑负载的微粒。
2. Enteric controlled-release pantoprazole-loaded microparticles prepared by using Eudragit S100 and poly(epsilon-caprolactone) blend. [J] . Raffin RP, Colome LM, Guterres SS, Pharmaceutical development and technology . 2007,第5期

机译：通过使用Eudragit S100和聚（ε-己内酯）共混物制备的肠溶控释负载的top托拉唑微粒。
3. Sodium pantoprazole-loaded enteric microparticles prepared by spray drying: effect of the scale of production and process validation. [J] . Raffin RP, Jornada DS, Re MI, International Journal of Pharmaceutics . 2006,第1期

机译：通过喷雾干燥制备的载有top托拉唑钠的肠溶微粒：生产规模的影响和工艺验证。
4. Pharmacokinetics evaluation of soft agglomerates containing enteric pantoprazole-loaded microparticles in dogs [C] . Annual meeting exposition of the Controlled Release Society . 2009

机译：药代动力学评估含有肠道泮托唑加载的微粒的软凝聚物在狗中的微粒
5. 1. Pharmacokinetic modeling and simulations of gastrointestinal transit effects on drug pharmacokinetics from enteric-coated pellet formulations and their applications. 2. Development of crushable enteric-coated formulations. 3. Development of leaky enteric-coated pellets formulations. [D] . Watanalumlerd, Prapoch. 2004

机译：1.胃肠道转运对肠溶微丸制剂中药物药代动力学的影响的药代动力学建模和模拟及其应用。 2.开发可压碎的肠溶衣制剂。 3.开发泄漏的肠溶丸剂。
6. Factors Contributing to Drug Release From Enteric-Coated Omeprazole Capsules: An In Vitro and In Vivo Pharmacokinetic Study and IVIVC Evaluation in Beagle Dogs [O] . Cheng Cui, Jiabei Sun, Xueqing Wang, 2020

机译：肠溶性奥美拉唑胶囊释放药物的因素：比格犬的体内和体外药代动力学研究及IVIVC评价
7. Factors Contributing to Drug Release From Enteric-Coated Omeprazole Capsules: An In Vitro and In Vivo Pharmacokinetic Study and IVIVC Evaluation in Beagle Dogs [O] . Cheng Cui, Jiabei Sun, Xueqing Wang, 2020

机译：肠涂层奥美拉唑胶囊的药物释放的因素：在比赛犬的体外和体内药代动力学研究和Ivivc评估

Pharmacokinetics evaluation of soft agglomerates containing enteric pantoprazole-loaded microparticles in dogs

摘要

著录项

相似文献

相关主题

期刊订阅