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Assessment of exposure of fuel station attendants to benzene, toluene and xylenes by analysis of end-exhaled air

机译:终端呼出空气分析评估燃料驻地服务员暴露于苯,甲苯和二甲苯的

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Exposure to benzene, toluene and p-, m-, o-xylene (BTX) was studied in 29 fuel station attendants and 16 office workers in Sri Lanka with the aim to assess the exposure level and identify potential exposure mitigating measures. Pre- and post-shift samples of end-exhaled air were collected and analyzed for BTX on a thermal desorption gas chromatography mass spectrometry system (TD-GC-MS). In addition, exposure was measured by personal air sampling using both diffusive and active sampling and analyzed by gas chromatography flame ionisation detection (GC-FID). Pre-shift BTX concentrations in end-exhaled air were higher in smokers compared to non-smokers (p<0.01) but storage of fossil fuels or motor vehicles in homes and staying overnight at the workplace did not contribute significantly. The median change from pre- to post-shift concentrations of benzene, toluene, m/p-xylene in end-exhaled air was 7.4,11.4, 0.79 and 0.71 ng/L in fuel station attendants and 1.5, 0.68, -0.06 and 0.59 ng/L in office workers, respectively. These concentrations were higher after self-reported dermal contact related to spills of gasoline (p<0.05). Median (range) breathing zone air concentrations were 608.8 (65.1 -1,957.7) |ig/m3 for benzene and 1,372 (267.5 - 3,548) u.g/m3 for toluene. Xylenes were not detected. Diffusive sampling overestimated results compared to active sampling by 26% for benzene and 10% for toluene. Benzene in exhaled air was moderately associated with benzene in the breathing zone (r=0.422; p<0.001). After adjustment for long work hours, 28% of the measured exposures exceeded the ACGIH threshold limit value (TLV) for an 8-h time-weighted average of 1.6 mg/m3 for benzene exposure. In conclusion, working as a fuel station attendant leads to inhalation exposure and occasional skin exposure to BTX. Smoking was identified as the most important co-exposure. Use of protective equipment and avoiding long work are expected to reduce exposure for benzene below the current TLV.
机译:在斯里兰卡的29个燃料站服务员和16名办公室工人中研究了暴露于苯,甲苯和P-,o - 二甲苯(BTX),目的是评估暴露水平并确定潜在的暴露缓解措施。收集并分析热解吸气相色谱质谱系统(TD-GC-MS)上的BTX后和移换后的终端呼出空气样品。此外,通过使用扩散和主动取样的个人空气采样来测量暴露,并通过气相色谱火焰离子电离检测(GC-FID)分析。与非吸烟者相比,吸烟者末端呼出空气中的换热浓度较高(P <0.01),但在房屋中储存化石燃料或机动车,在工作场所保持过夜并没有显着贡献。燃料站伴者中苯甲苯,甲苯,甲苯后血液浓度的中值变化为7.4,11.4,0.79和0.71 ng / l,燃料站函数,1.5,0.68,-0.06和0.59分别在办公室工作人员中的ng / l。自我报告的皮肤接触后,这些浓度较高,与汽油溢出有关(P <0.05)。中位数(范围)呼吸区空气浓度为608.8(65.1 -1,957.7)| Ig / M3用于苯,1,372(267.5-3,548)U.g / M3用于甲苯。未检测到二甲苯。扩散采样高估结果与苯的活性取样相比,苯的26%和甲苯的10%。呼出空气中的苯与呼吸区中的苯相当相关(r = 0.422; p <0.001)。调整长工作时间后,28%的测量曝光超过ACGIH阈值限值(TLV),用于苯暴露的8小时递增平均为1.6mg / m 3。总之,作为燃料驻地服务员的工作导致吸入暴露和偶尔的皮肤暴露于BTX。吸烟被认为是最重要的共同暴露。使用防护装备和避免长期工作预计将减少当前TLV以下苯的暴露。

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