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首页> 外文会议>Multimodal biomedical imaging XII >Investigation of burn effect on skin using simultaneous Raman-Brillouin spectroscopy, and fluorescence microspectroscopy
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Investigation of burn effect on skin using simultaneous Raman-Brillouin spectroscopy, and fluorescence microspectroscopy

机译：同时使用拉曼布里渊光谱和荧光显微技术研究皮肤烧伤效果

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摘要

Burns are thermal injuries that can completely damage or at least compromise the protective function of skin, and affect the ability of tissues to manage moisture. Burn-damaged tissues exhibit lower elasticity than healthy tissues, due to significantly reduced water concentrations and plasma retention. Current methods for determining burn intensity are limited to visual inspection, and potential hospital x-ray examination. We present a unique confocal microscope capable of measuring Raman and Brillouin spectra simultaneously, with concurrent fluorescence investigation from a single spatial location, and demonstrate application by investigating and characterizing the properties of burn-afflicted tissue on chicken skin model. Raman and Brillouin scattering offer complementary information about a material's chemical and mechanical structure, while fluorescence can serve as a useful diagnostic indicator and imaging tool. The developed instrument has the potential for very diverse analytical applications in basic biomedical science and biomedical diagnostics and imaging.
机译：灼伤是热损伤，可完全破坏或至少损害皮肤的保护功能，并影响组织管理水分的能力。灼伤损坏的组织由于水浓度和血浆保留量显着降低，因此比健康组织的弹性低。当前确定烧伤强度的方法仅限于目视检查和可能的医院X射线检查。我们提出了一种独特的共聚焦显微镜，能够同时测量拉曼光谱和布里渊光谱，同时从单个空间位置进行荧光研究，并通过研究和表征烧伤组织在鸡皮模型上的特性来证明其应用。拉曼和布里渊散射提供有关材料化学和机械结构的补充信息，而荧光可以用作有用的诊断指示剂和成像工具。开发的仪器具有在基础生物医学以及生物医学诊断和成像领域非常广泛的分析应用潜力。

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  • 来源
    《Multimodal biomedical imaging XII》|2017年|1005705.1-1005705.6|共6页
  • 会议地点 San Francisco(US)
  • 作者

    Zachary Coker; Zhaokai Meng; Maria Troyanova-Wood; Andrew Traverso; Charles Ballmann; Georgi Petrov; Bennett L. Ibey; Vladislav Yakovlev;

  • 作者单位

    Texas AM University, 3120 TAMU, College Station, TX, USA 77843,Radio Frequency Bioeffects Branch, Bioeffects Division, Human Effectiveness Directorate, 711th Human Performance Wing, Air Force Research Laboratory, JBSA Fort Sam Houston, TX;

    Texas AM University, 3120 TAMU, College Station, TX, USA 77843;

    Texas AM University, 3120 TAMU, College Station, TX, USA 77843;

    Texas AM University, 3120 TAMU, College Station, TX, USA 77843;

    Texas AM University, 3120 TAMU, College Station, TX, USA 77843;

    Texas AM University, 3120 TAMU, College Station, TX, USA 77843;

    Radio Frequency Bioeffects Branch, Bioeffects Division, Human Effectiveness Directorate, 711th Human Performance Wing, Air Force Research Laboratory, JBSA Fort Sam Houston, TX;

    Texas AM University, 3120 TAMU, College Station, TX, USA 77843;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Brillouin Spectroscopy; Raman Spectroscopy; Skin burns; Wound Imaging and Monitoring;

    机译：布里渊光谱;拉曼光谱皮肤灼伤；伤口成像和监测；;

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