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In-situ pre- and postoperative optical resolution of the lens and pseudo-phacos: a preliminary report

机译：晶状体和假性粘膜的术前和术后光学分辨率：初步报告

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Abstract: The effect of novel intraocular implants and refractive surgical techniques on visual acuity and contrast sensitivity is normally determined by the outcome of human clinical trials. Even if intraocular lenses (IOL) are optically `bench tested' prior to implantation, and their contribution to the patient's vision modeled by computer simulation, the clinical outcome is often poorer than mathematically predicted. This is due in large part to the approximations made in the schematic eye used for computation and the biological variables, such as iris geometry, the implant centration, and location with respect to the three-dimensional position of the visual axis and foveal plane. In vitro laboratory optical testing of novel IOLs and lens refractive procedures, such as capsular bag refilling and inflatable balloons, are non-existent. As animal experiments cannot resolve this dilemma, we took a new in vitro approach at assessing the vision of surgically modified and/or implanted human eyes. Using stock parts, a new optical instrument was built to measure the in situ optical resolution and OMTF of fresh cadaver eyes and to comparatively assess novel surgical techniques and implants by pre- and postoperative optical measurements of the retinal image. !17
机译：摘要：新型眼内植入物和屈光手术技术对视敏度和对比敏感度的影响通常取决于人类临床试验的结果。即使在植入前对人工晶状体（IOL）进行了光学“基准测试”，并且通过计算机模拟对人工晶状体对患者视力的贡献进行了模拟，临床结果通常也比数学上预测的要差。这在很大程度上是由于用于计算的示意图眼和生物变量（例如虹膜几何形状，植入物中心以及相对于视轴和中央凹平面的三维位置的位置）中的近似值。尚不存在新颖的IOL和晶状体屈光程序的体外实验室光学测试，例如囊袋填充和充气球囊。由于动物实验无法解决这一难题，因此我们采用了一种新的体外方法来评估经过手术改造和/或植入的人眼的视力。使用库存零件，制造了一种新的光学仪器，用于测量新鲜尸眼的原位光学分辨率和OMTF，并通过对视网膜图像进行术前和术后光学测量来比较评估新型手术技术和植入物。 ！17

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