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首页> 外文会议>Optical Coherence Tomography and Coherence Techniques III; Progress in Biomedical Optics and Imaging; vol.8 no.40; Proceedings of SPIE-The International Society for Optical Engineering; vol.6627 >Quantification of the Outer Retinal Layers: Correlation to Visual Acuity in Healthy Subjects and Patients with Central Serous Chorioretinopathy
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Quantification of the Outer Retinal Layers: Correlation to Visual Acuity in Healthy Subjects and Patients with Central Serous Chorioretinopathy

机译：视网膜外层的定量：与健康主体和中央浆液性脉络膜视网膜病变患者的视力相关

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Purpose: Quantification of outer retinal layers in humans. Method: 11 eyes in healthy subjects and 3 eyes in patients after resolution of central serous chorioretinopathy (CSCR). Multiple line scans were obtained using OCT Stratus and scans were registered and averaged to enhance contrast. The distance from the inner-outer segment junction to the posterior part of the retinal pigment epithelium (RPE-OS_(complex)) was calculated. In addition, the reflectance of the outer photoreceptor layer in the foveal center was compared to that peripheral to the fovea. Results: Mean thickness of the RPE-OS_(complex) in healthy subjects was 77.3 μm, in CSCR 52.9 μm. The thickness of the RPE-OS_(complex) was significantly correlated to visual acuity (r=0.95, p < 0.01). The ratio of reflectance (fovea/parafovea) was 1.06 in healthy subjects, 1.18 in CSCR eyes. Conclusion: The RPE-OS_(complex) thickness was markedly reduced in eyes after resolution of CSCR and highly correlated to the visual acuity, the correlation to total foveal thickness was less. An increased backscatter was seen in CSCR, probably due to photoreceptor disorganization and atrophy.
机译：目的：量化人类视网膜外层。方法：健康受试者11眼，中枢浆液性脉络膜视网膜病变（CSCR）消退后，患者3眼。使用OCT Stratus获得多行扫描，并记录扫描结果并取平均值以增强对比度。计算从内-外节连接点到视网膜色素上皮的后部的距离（RPE-OS_（复合体））。另外，将中央凹中央的外部感光体层的反射率与中央凹周边的反射率进行比较。结果：健康受试者中RPE-OS_（复合物）的平均厚度为77.3μm，在CSCR中为52.9μm。 RPE-OS_（复合物）的厚度与视敏度显着相关（r ＝ 0.95，p ＜0.01）。在健康受试者中，反射率（中央凹/副中央凹）的比率为1.06，在CSCR眼睛中为1.18。结论：CSCR消退后，RPE-OS_（复合物）的厚度明显减少，并且与视力高度相关，而与总中央凹厚度的相关性较小。在CSCR中看到的反向散射增加，可能是由于感光器的混乱和萎缩。

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