Quantitative Estimation of IL-6 in Serum/Plasma Samples Using a Rapid and Cost-Effective Fiber-Optic dip-probe

机译：使用快速且经济有效的光纤浸入探针对血清/血浆样品中的IL-6进行定量估计

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A rapid and cost-effective combination tapered fiber-optic biosensor (CTFOB) dip-probe was used for quantitative estimation of interleukin (IL)-6 in serum/plasma samples. Sandwich immunoassay was used as the detection technique. Probes could successfully detect presence of IL-6 in two serum samples, non-neoplastic autoimmune patient (lupus) sample and lymphoma patient sample. The estimated amount of IL-6 in lupus patient sample was 4.8 ± 0.9 pM and in lymphoma patient sample was 2 + 1 pM. It is demonstrated that the developed CTFOB dip-probe is capable of quantitative estimation of proteins in serum/plasma samples with high specificity.

机译：一种快速且经济高效的组合锥形光纤生物传感器（CTFOB）浸入探针用于定量评估血清/血浆样品中的白介素（IL）-6。夹心免疫测定被用作检测技术。探针可以成功检测两种血清样本中的IL-6的存在：非肿瘤性自身免疫患者（狼疮）样本和淋巴瘤患者样本。狼疮患者样品中IL-6的估计量为4.8±0.9 pM，淋巴瘤患者样品中IL-6的量为2 +1 pM。已证明开发的CTFOB浸入探针能够以高特异性定量评估血清/血浆样品中的蛋白质。

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来源
《Optical fibers and sensors for medical diagnostics and treatment applications X》|2010年|P.75590G.1-75590G.5|共5页
会议地点 San Francisco CA(US)
作者
Chun Wei Wang; Upender Manne; Vishnu B. Reddy; Rakesh Kapoor;
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作者单位

Departments of Physics,University of Alabama at Birmingham, Birmingham, AL 35294;

Departments of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294;

Departments of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294;

Departments of Physics,University of Alabama at Birmingham, Birmingham, AL 35294;

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会议组织
原文格式 PDF
正文语种 eng
中图分类医用物理学;
关键词
fiber-optic; fluorescence; IL-6; cytokine; serum; lupus; lymphoma;

机译：光纤荧光IL-6；细胞因子血清;狼疮;淋巴瘤;

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专利

1. Errata: Development of combination tapered fiber-optic biosensor dip probe for quantitative estimation of interleukin-6 in serum samples [J] . Chun Wei Wang Upender Manne Vishnu B. Reddy Denise K. Oelschlager Venkat R. Katkoori William E. Grizzle and Rakesh Kapoor journal of biomedical optics . 2011,第1期

机译：勘误：用于定量评估血清样品中白介素-6的组合锥形光纤生物传感器浸入式探针的开发
2. Development of combination tapered fiber-optic biosensor dip probe for quantitative estimation of interleukin-6 in serum samples [J] . Chun Wei Wang, Upender Manne, Vishnu B. Reddy, Journal of biomedical optics . 2010,第6期

机译：用于定量评估血清样品中白介素6的组合锥形光纤生物传感器浸入式探针的开发
3. Cost-Effective Automated Preparation of Serum Samples for Reproducible Quantitative Clinical Proteomics [J] . Lee Jihyeon, Kim Hyunsoo, Sohn Areum, Journal of proteome research . 2019,第5期

机译：用于可重复定量临床蛋白质组学的血清样品的经济高效的自动制备
4. Quantitative Estimation of IL-6 in Serum/Plasma Samples Using a Rapid and Cost-Effective Fiber-Optic dip-probe [C] . Chun Wei Wang, Upender Manne, Vishnu B. Reddy, SPIE Conference on Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications . 2010

机译：使用快速和经济高效的光纤倾析探针定量估计血清/等离子体样品中的IL-6
5. Implementation of Low Cost, High-Throughput and High Sensitive Biomarker Detection Technique in Serum/Plasma Samples by Integrating Dielectrophoresis and Fluorescence Based Platform [D] . Logeeshan, Velmanickam 2019

机译：介电电泳与荧光平台整合实现血清/血浆样品中低成本，高通量，高灵敏度的生物标志物检测技术
6. Quantitative Estimation of IL-6 in Serum/Plasma Samples Using a Rapid and Cost-Effective Fiber-Optic dip-probe [O] . Chun Wei Wang, Upender Manne, Vishnu B. Reddy, -1

机译：使用快速和经济高效的光纤倾析探针定量估计血清/等离子体样品中的IL-6
7. Errata: Development of combination tapered fiber-optic biosensor dip probe for quantitative estimation of interleukin-6 in serum samples [O] . Wang, Chun Wei, Manne, Upender, Reddy, Vishnu B., 2011

机译：勘误：用于定量评估血清样品中白介素-6的组合锥形光纤生物传感器浸入式探针的开发

Quantitative Estimation of IL-6 in Serum/Plasma Samples Using a Rapid and Cost-Effective Fiber-Optic dip-probe

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