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Optical Characterization of Pancreatic Normal and Tumor Tissues with Double Integrating Sphere System

机译:双积分球系统对胰腺正常和肿瘤组织的光学表征

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In order to develop minimally invasive, fast and precise diagnostic and therapeutic methods in medicine by using optical methods, first step is to examine how the light propagates, scatters and transmitted through medium. So as to find out appropriate wavelengths, it is required to correctly determine the optical properties of tissues. The aim of this study is to measure the optical properties of both cancerous and normal ex-vivo pancreatic tissues. Results will be compared to detect how cancerous and normal tissues respond to different wavelengths. Double-integrating-sphere system and computational technique inverse adding doubling method (IAD) were used in the study. Absorption and reduced scattering coefficients of normal and cancerous pancreatic tissues have been measured within the range of 500-650 nm. Statistical significant differences between cancerous and normal tissues have been obtained at 550 ran and 630 nm for absorption coefficients. On the other hand; there were no statistical difference found for scattering coefficients at any wavelength.
机译:为了通过使用光学方法开发医学上微创,快速和精确的诊断和治疗方法,第一步是检查光如何通过介质传播,散射和传输。为了找出合适的波长,需要正确地确定组织的光学性质。这项研究的目的是测量癌性和正常的离体胰腺组织的光学特性。将比较结果以检测癌组织和正常组织对不同波长的反应。本研究采用双积分球系统和计算技术反加倍法(IAD)。已在500-650 nm范围内测量了正常和癌性胰腺组织的吸收系数和降低的散射系数。癌组织和正常组织之间的统计显着性差异已在550 nm和630 nm处获得了吸收系数。另一方面;在任何波长下,散射系数均无统计学差异。

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