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首页> 外文会议>Optical tomography and spectroscopy of tissue XII >Preliminary results of miniaturized and robust Ultrasound guided diffuse optical tomography system for breast cancer detection
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Preliminary results of miniaturized and robust Ultrasound guided diffuse optical tomography system for breast cancer detection

机译：小型，坚固耐用的超声引导散射光学层析成像系统用于乳腺癌检测的初步结果

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According to the World Health Organization, breast cancer is the most common cancer among women worldwide, claiming the lives of hundreds of thousands of women each year. Near infrared diffuse optical tomography (DOT) has demonstrated a great potential as an adjunct modality for differentiation of malignant and benign breast lesions and for monitoring treatment response of patients with locally advanced breast cancers. The path toward commercialization of DOT techniques depends upon the improvement of robustness and user-friendliness of this technique in hardware and software. In the past, our group have developed three frequency domain prototype systems which were used in several clinical studies. In this study, we introduce our newly under development US-guided DOT system which is being improved in terms of size, robustness and user friendliness by several custom electronic and mechanical design. A new and robust probe designed to reduce preparation time in clinical process. The processing procedure, data selection and user interface software also updated. With all these improvements, our new system is more robust and accurate which is one step closer to commercialization and wide use of this technology in clinical settings. This system is aimed to be used by minimally trained user in the clinical settings with robust performance. The system performance has been tested in the phantom experiment and initial results are demonstrated in this study. We are currently working on finalizing this system and do further testing to validate the performance of this system. We are aiming toward use of this system in clinical setting for patients with breast cancer.
机译：根据世界卫生组织的资料，乳腺癌是全世界女性中最常见的癌症，每年夺去数十万人的生命。近红外漫射光学层析成像（DOT）已显示出巨大的潜力，可作为辅助手段来区分恶性和良性乳腺病变以及监测局部晚期乳腺癌患者的治疗反应。 DOT技术商业化的道路取决于该技术在硬件和软件中的鲁棒性和用户友好性的提高。过去，我们小组已经开发了三个频域原型系统，这些系统已在多个临床研究中使用。在这项研究中，我们介绍了我们最新开发的美国指导的DOT系统，该系统在尺寸，坚固性和用户友好性方面已通过几种定制的电子和机械设计得到了改进。一种新颖而坚固的探头，旨在减少临床过程中的准备时间。处理程序，数据选择和用户界面软件也进行了更新。通过所有这些改进，我们的新系统更加健壮和准确，这距该技术的商业化和在临床环境中的广泛应用仅一步之遥。该系统旨在由训练有素的用户在临床环境中以稳定的性能使用。系统性能已在幻像实验中进行了测试，并且在此研究中证明了初步结果。我们目前正在努力完成该系统的定型工作，并进行进一步的测试以验证该系统的性能。我们的目标是在乳腺癌患者的临床环境中使用该系统。

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