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Optically driven micromachines for biotechnological applications

机译:用于生物技术应用的光驱微机

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We have shown earlier that photopolymerization offers a relatively simple method to produce microscopic particles of arbitrary shape that are practical to expand the possibilities of optical manipulation. Propeller shaped micrometer sized rotors are rotated in optical tweezers, while fiat objects are oriented in traps formed by linearly polarized light. Such elements and the possibilities opened up by their use would find numerous applications in lab-on-a-chip devices. We have extended these methods by developing new elements for applications. We have built microscopic wheels and gears that have a central flat component so that its rotational position can be controlled by linearly polarized light. These rotors are rotated by rotating the polarisation of the light. Such gears can be used as actuators of more complex micromechanical devices (pumps, valves,) also built by photopolymerization in a single process. Important component of such devices are gears rotating on fixed axes, readily built by the method. An alternative way of optically actuating rotating devices by light is the illumination of cogwheel shaped rotors from a tangential direction. The advantage of this latter approach is that the whole system (i.e. the rotors on axes and optical waveguides that carry the actuating as well as possibly the sensing light) can be built as an integrated system in a single process. Such devices would not need optical tweezers and thus bulky microscopes for actuation, significantly reducing the complexity of eventual lab-on-a-chip devices.. Operational examples will be demonstrated and the properties of the different approaches will be compared.
机译:前面我们已经表明,光聚合提供了一种相对简单的方法来生产任意形状的微观粒子,这些粒子对于扩大光学操作的可能性是实用的。螺旋桨形状的微米级转子在光镊中旋转,而法线物体则在由线性偏振光形成的陷阱中定向。这样的元件及其使用带来的可能性将在片上实验室设备中找到许多应用。通过开发新的应用程序元素,我们扩展了这些方法。我们制造了具有中心扁平部件的微型轮和齿轮,以便可以通过线性偏振光控制其旋转位置。通过旋转光的偏振来旋转这些转子。此类齿轮可用作更复杂的微机械装置(泵,阀)的致动器,这些装置也可以通过光聚合在单个过程中构建。这种装置的重要组成部分是固定轴旋转的齿轮,该齿轮很容易通过该方法制造。用光光学驱动旋转装置的另一种方式是从切线方向照亮齿轮状的转子。后一种方法的优点在于,整个系统(即,轴上的转子和承载驱动光以及可能包含传感光的光波导)可以在单个过程中构建为集成系统。这样的设备不需要光镊子,因此不需要笨重的显微镜来致动,从而大大降低了最终的芯片实验室设备的复杂性。将演示操作示例并比较不同方法的特性。

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