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首页> 外文会议>Proceedings of Life in space for life on earth >EFFECTS OF ULOADIG AD RELOADIG O EXPRESSIOS OF SK MUSCLE MEMBRAE PROTEIS I MICE
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EFFECTS OF ULOADIG AD RELOADIG O EXPRESSIOS OF SK MUSCLE MEMBRAE PROTEIS I MICE

机译：肌腱蛋白的表达U / tLOADA tG A tD RELOADI tG O t EXS的影响

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摘要

Effects of unloading and reloading on the expressionrnlevels of tripartite motif-containing 72 (TRIM72) andrncaveolin-3 (Cav-3) of soleus muscle in mice wererninvestigated. Male C57BL/6J mice (11-week old) werernrandomly assigned to control and hindlimb-suspendedrngroups. Some of mice in hindlimb-suspended group werernsubjected to continuous hindlimb suspension (HS) for 2rnweeks with or without 7 days of ambulation recovery.rnFollowing HS, the muscle weight and protein expressionrnlevels of TRIM72 and Cav-3 in soleus were decreased.rnOn the other hand, the gradual increases in muscle mass,rnTRIM72 and Cav-3 were observed after reloadingrnfollowing HS. Therefore, it was suggested thatrnmechanical loading played a key role in a regulatoryrnsystem for protein expressions of TRIM72 and Cav-3.
机译：研究了装卸对小鼠比目鱼肌中含三方基序的72（TRIM72）和caveolin-3（Cav-3）的表达水平的影响。随机将雄性C57BL / 6J小鼠（11周龄）分为对照组和后肢暂停组。后肢悬吊组的一些小鼠接受连续后肢悬吊（HS）2rnweek，有或没有7天的运动恢复。rnsHS之后，比目鱼肌中TRIM72和Cav-3的肌肉重量和蛋白质表达水平降低。在HS负荷后，观察到肌肉质量逐渐增加，TRIM72和Cav-3逐渐增加。因此，有人提出，机械负荷在TRIM72和Cav-3蛋白表达的调节系统中起关键作用。

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  • 会议地点 Aberdeen(GB)
  • 作者

    Y. Ohno; A. Ikuta; A. Goto; T. Sugiura; Y. Ohira; T. Yoshioka; K. Goto;

  • 作者单位

    Laboratory of Physiology, School of Health Sciences, Toyohashi SOZO University, 20-1 Matsushita, Ushikawa, Toyohashi, Aichi 440-8511, Japan, Email: yohno@sozo.ac.jp;

    Department of Physiology, Graduate School of Health Sciences, Toyohashi SOZO University, 20-1 Matsushita, Ushikawa, Toyohashi, Aichi 440-8511, Japan, Email: r0672601@sc.sozo.ac.jp;

    Department of Physiology, Graduate School of Health Sciences, Toyohashi SOZO University, 20-1 Matsushita, Ushikawa, Toyohashi, Aichi 440-8511, Japan, Email: r0772710@sc.sozo.ac.jp;

    Department of Exercise and Health Sciences, Faculty of Education, Yamaguchi Univ., 1677-1 yoshida, Yamaguchi, Yamaguchi 753-8513, Japan, Email: takahito@yamaguchi-u.ac.jp;

    Graduate School of Medicine, Osaka University, 1-17 machikaneyama, Toyonaka, Osaka 560-0043, Japan, Email: ohira@space.hss.osaka-u.ac.jp;

    Hirosaki Gakuin University, 13-1 minori, Hirosaki, Aomori 036-8577, Japan, Email:yoshioka_toshitada@hirogaku-u.ac.jp;

    Department of Physiology, Graduate School of Health Sciences, Toyohashi SOZO University, 20-1 Matsushita, Ushikawa, Toyohashi, Aichi 440-8511, Japan, Email: gotok@sepia.ocn.ne.jp;

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