Field-based multiplex and quantitative assay platforms for diagnostics

机译：基于现场的多重和定量分析平台，用于诊断

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The U.S. military has a continued interest in the development of handheld, field-usable sensors and test kits for a variety of diagnostic applications, such as traumatic brain injury (TBI) and infectious diseases. Field-use presents unique challenges for biosensor design, both for the readout unit and for the biological assay platform. We have developed robust biosensor devices that offer ultra-high sensitivity and also meet field-use needs. The systems under development include a multiplexed quantitative lateral flow test strip for TBI diagnostics, a field test kit for the diagnosis of pathogens endemic to the Middle East, and a microfluidic assay platform with a label-free reader for performing complex biological automated assays in the field.

机译：美军一直对开发手持式，现场可用的传感器和测试套件的兴趣不断，这些传感器和测试套件可用于各种诊断应用，例如脑外伤（TBI）和传染病。对于读出单元和生物测定平台而言，现场使用对生物传感器设计提出了独特的挑战。我们已经开发了坚固的生物传感器设备，这些设备可提供超高灵敏度并满足现场使用需求。正在开发的系统包括用于TBI诊断的多重定量侧流测试条，用于诊断中东地方病原体的现场测试套件以及带有无标签读取器的微流分析平台，该平台可用于在实验室中执行复杂的生物自动化分析领域。

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《Sensing technologies for global health, military medicine, disaster response, and environmental monitoring; and Biometric technology for human identification VIII》|2011年|p.1-11|共11页
会议地点 Orlando FL(US);Orlando FL(US)
作者
Srivatsa Venkatasubbarao; C. Edward Dixon; Russell Chipman; Axel Scherer; Manal Beshay; Lothar U. Kempen; Jai Ganesh Chandra Sekhar; Hong Yan; Ava Puccio; David Okonkwo; Stephen McClain; Noah Gilbert; Saurabh Vyawahare;
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作者单位

Intelligent Optical Systems, Inc. (USA);

Univ. of Pittsburgh (USA);

The Univ. of Arizona (USA);

California Institute of Technology (USA);

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会议组织
原文格式 PDF
正文语种 eng
中图分类生物工程学（生物技术）;遥感技术的应用;
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机译：可扩展的转录分析程序—用于基因表达分析和分子诊断的多重定量实时聚合酶链反应平台
3. Scalable transcriptional analysis routine--multiplexed quantitative real-time polymerase chain reaction platform for gene expression analysis and molecular diagnostics. [J] . Garcia EP, Dowding LA, Stanton LW, The Journal of molecular diagnostics: JMD . 2005,第4期

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4. Field-based multiplex and quantitative assay platforms for diagnostics [C] . Srivatsa Venkatasubbarao, C. Edward Dixon, Russell Chipman, Conference on sensing technologies for global health, military medicine, disaster response, and environmental monitoring . 2011

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5. Development of silicon photonic microring resonator biosensors for multiplexed cytokine assays and in vitro diagnostics. [D] . Luchansky, Matthew Sam. 2012

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Field-based multiplex and quantitative assay platforms for diagnostics

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