声明
致谢
LIST OF ABBREVIATIONS
CHAPTER 1 GENERAL INTRODUCTION
1.1.Background
1.2.Objectives
CHAPTER 2 LITERATURE REVIEW
2.1.1.Classification of biosurfactants
2.1.2.Mannosylerythritol lipids
2.1.3.Biosurfactants in nanomaterials applications
2.2.Applications of nanomaterials
2.2.1.Nanomaterials as antibacterial agents
2.2.2.Nanomaterials as anticancer agents
2.2.3.Nanomaterials as antioxidants agents
2.3.Metal nanoparticles
2.6.Enzyme Immobilization
2.8.Genipin
2.9.Gum arabic
CHAPTER 3 SYNTHESIS OF GOLD NANOPARTICLES DERIVED FROM MANNOSYLERYTHRITOL LIPID AND EVALUATION OF THEIR BIOACTIVITIES
3.2.Materials and methods
3.2.3.MEL production by resting cells cultivation
3.2.4.Biosynthesis of gold nanoparticles
3.2.5.Statistical analysis
3.3.1.Production and characterization of MEL
3.3.2.Characterization of biosynthesized MEL-AuNPs
3.3.3.Antibacterial activity of biosynthesized MEL-AuNPs
3.3.4.Anticancer activity of MEL-AuNPs against the HepG2 cell line
3.3.5.Antioxidant activity of MEL-AuNPs
3.4.Conclusions
CHAPTER 4 COMPARATIVE STUDY OF ANTIDIABETIC, BACTERICIDAL， AND ANTITUMOR ACTIVITIES OF MEL@AGNPS, MEL@ZNONPS, AND AGZNO/MEL/GA NANOCOMPOSITES PREPARED BY USING MEL AND GUM ARABIC
4.1.Introduction
4.2.Materials and Methods
4.2.2.Synthesis of nanocomposites
4.2.3.Antidiabetic activity
4.2.4.Bactericidal efficacy test
4.2.5.Antitumor Activity
4.3.1.Characterization of nanocomposites
4.3.2.Inhibition of a-amylase and a-glucosidase
4.3.3.Bactericidal potential studies
4.4.Cell viability assay
4.5.Conclusions
CHAPTER 5 FABRICATION, CHARACTERIZATION, AND ANTI-VREF ACTIVITY OF BIOCOMPATIBLE IMMOBILIZED-LYSOZYME ON CHITOSAN/SILVER MICROBEADS COMPLEX
5.1.Introduction
5.2.Materials and methods
5.2.4.Fabrication of Ag@CS-MBs complex
5.2.8.Antibacterial studies of the Ag@LZ/CS-MBs complex
5.2.9.Biocompatibility assay
5.2.10.Statistical analysis
5.3.1.Characterization of Ag@LZ/GNCS-MBs complex
5.3.2.Lysozyme immobilization
5.3.3.Bactericidal studies
5.3.4.Biocompatibility assay
5.4.Conclusions
CHAPTER 6 GENERAL CONCLUSIONS AND FUTURE PROSPECTIVE
6.2.Future Prospective
参考文献
LIST OF PUBLICATIONS
Author’s Resume
浙江大学;
