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Comparison of calcium sulfate and bovine collagen barriers for ridge augmentation in the canine.

机译：犬牙and增高的硫酸钙和牛胶原屏障的比较。

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摘要

Background. Calcium sulfate (CS) is a biologically compatible, osteo-conductive graft material that may bind underlying bone graft and provide space maintenance. The purpose of this study was to evaluate CS as a barrier compared to a collagen membrane (CM) for augmentation of a standardized surgically created ridge defect.; Methods. Six foxhounds were used as subjects. Extractions of mandibular premolars 1, 2, 3 and 4 were performed bilaterally. After 8 weeks, standardized osseous ridge defects were created using a 6 mm trephine. A total of 24 defects were created and allocated to three groups: autogenous bone covered by CM, autogenous bone covered by CS barrier, and non-augmented control sites (Ctrl). Five animals were sacrificed 12 weeks after the augmentation procedures, and sites were evaluated histologically for total area, width, percentage of bone and cortical bone thickness.; Results. Twenty sites were available for evaluation. All sites exhibited some bony fill within the defect. Comparison of findings revealed no statistically significant differences in mean total area (CM=12.2 mm2, Ctrl=11.9 mm2, CS=11.6 mm2), width, percentage of bone (CS=38.2%, Ctrl=37.9%, CM=36.3%) or cortical bone thickness (Ctrl=0.49-1.43 mm, CS=0.56-1.38 mm, CM=0.41-1.06 mm).; Conclusions. The results of this study indicated that osseous regeneration of an alveolar ridge defect was comparable for sites treated using autogenous bone graft with a barrier of calcium sulfate or collagen membrane. There were no statistically significant differences in terms of surface area, percent bone fill, width, or cortical bone thickness within the defect.; Key words. Guided bone regeneration, ridge augmentation, calcium sulfate, collagen membrane
机译：背景。硫酸钙（CS）是生物相容的骨传导性移植材料，可以结合下面的骨移植物并提供空间维持。这项研究的目的是评估CS与胶原膜（CM）相比是否可作为屏障，以增强标准化的手术产生的脊缺损。方法。以六只猎狗为对象。双侧下颌前磨牙1、2、3和4的提取。 8周后，使用6 mm的苯丙胺创建标准的骨缺损。总共创建了24个缺陷并将其分配给三组：CM覆盖的自体骨，CS障碍物覆盖的自体骨和非增强控制部位（Ctrl）。在增强手术后12周处死5只动物，并通过组织学评估部位的总面积，宽度，骨百分比和皮质骨厚度。结果。有20个站点可供评估。所有部位在缺损处均显示出骨质填充。结果比较表明，平均总面积（CM = 12.2平方毫米，Ctrl = 11.9平方毫米，CS = 11.6平方毫米），宽度和骨骼百分比（CS = 38.2％，Ctrl = 37.9％，CM = 36.3％）无统计学差异。或皮质骨厚度（Ctrl = 0.49-1.43 mm，CS = 0.56-1.38 mm，CM = 0.41-1.06 mm）;结论。这项研究的结果表明，与使用硫酸钙或胶原膜屏障的自体骨移植治疗的部位相比，牙槽缺损的骨再生是可比的。缺陷内的表面积，骨填充百分比，宽度或皮质骨厚度方面无统计学差异。关键字引导性骨再生，ridge扩张，硫酸钙，胶原膜

著录项

  • 作者

    Heaton, Matthew L.;

  • 作者单位

    The Texas A&M University System Health Science Center.;

  • 授予单位 The Texas A&M University System Health Science Center.;
  • 学科 Health Sciences Dentistry.
  • 学位 M.S.
  • 年度 2007
  • 页码 60 p.
  • 总页数 60
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 口腔科学;
  • 关键词

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